Angelini G, Antolini G, Bovo P, Cavallini G, Fratta Pasini A, Lavarini E, Piubello W, Rigo L, Scuro L A
Clinica Medica, Università di Verona, Policlinico Borgo Roma, Italy.
Int J Pancreatol. 1987 Oct-Dec;2(5-6):305-10. doi: 10.1007/BF02788430.
The aim of this study was to evaluate the endoscopic retrograde pancreatographic (ERP) findings in respect of alcohol intake. Two hundred eleven patients consecutively submitted to ERP for upper abdominal symptomatology, with suspected pancreatic disease (SPD; 79 patients) or without (NSPD; 132 subjects), were classified in 3 groups of different ethanol intake: 1 (0-40 g/day), 2 (41-80 g/day), 3 (more than 80 g/day). The following conclusions could be drawn: (1) the frequency of ERP changes increases with the increase of alcohol intake both in SPD (34.6-63.8%) and NSPD (8.2-29.8%); (2) the frequency of pancreatic cancer was not related to alcohol intake, but in NSPD it was about 2-fold that in SPD: 12/132 (9.1%) vs 4/79 (5.06%); (3) a pancreatic morphological assessment, by means of ERP or other imaging techniques, should be performed in every subject with upper abdominal pain of unknown origin both in alcoholics (for the high incidence of chronic pancreatitis) and in non-alcoholics (for the risk of pancreatic cancer, which approximates 10%).
本研究旨在评估酒精摄入量与内镜逆行胰胆管造影（ERP）结果之间的关系。连续211例因上腹部症状接受ERP检查的患者，根据是否怀疑患有胰腺疾病（SPD；79例患者）分为两组，再根据乙醇摄入量不同分为3组：1组（0 - 40克/天）、2组（41 - 80克/天）、3组（超过80克/天）。可得出以下结论：（1）无论是SPD组（34.6 - 63.8%）还是非SPD组（NSPD；8.2 - 29.8%），ERP改变的频率均随酒精摄入量的增加而升高；（2）胰腺癌的发生率与酒精摄入量无关，但在NSPD组中约为SPD组的2倍：12/132（9.1%）对4/79（5.06%）；（3）对于不明原因上腹部疼痛的患者，无论是否饮酒（酗酒者慢性胰腺炎发病率高，非酗酒者胰腺癌风险约为10%），均应通过ERP或其他影像学技术进行胰腺形态学评估。
