[The anatomical and histological investigation of the pancreas in the 19th century and till the discovery of insulin (1921). 4. The pancreas-research after the discovery of pancreas-diabetes (1889) till the discovery of insulin].

In this study is the history of the pancreas-research between 1889 and 1921 described. In this period are any important discoverys detected: The islets have 2 cell types (TSCHASSOW-NIKOW 1900, 1906); the connection between diabetes mellitus and islet-alterations (OPIE 1900); the independence of islets on exocrine parenchyma (SCHULZE 1900); the discovery of internal secretion (BAYLISS, STARLING 1902) and the regeneration of islets in mammals and the man (KYRLE 1908; WEICHSELBAUM 1908 in independent publications.