Laboratório de Imunologia e Microbiologia, Escola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul, PUCRS, Porto Alegre, Brazil.
Programa de Pós-graduação em Odontologia, Escola de Ciências da Saúde e da Vida, Pontifícia Universidade Católica do Rio Grande do Sul, PUCRS, Porto Alegre, Brazil.
Am J Trop Med Hyg. 2023 Mar 20;108(5):1071-1077. doi: 10.4269/ajtmh.22-0580. Print 2023 May 3.
The irrational use of antimicrobial drugs has become a serious epidemiological problem due to the development of bacterial resistance, causing consequences for global health. In dentistry, antibiotics are the second most common pharmacological class prescribed. Thus, we evaluated the use of antimicrobial prophylaxis by dentists in Porto Alegre, Brazil, and the metropolitan region using an online questionnaire. Dentists were asked to complete an anonymous questionnaire concerning antimicrobial prescription. The questionnaire was prepared on the Microsoft Forms platform and shared with dentists through social media and was available for a period of 40 days. The questionnaire was answered by 82 dentists, and 85.3% of them reported prescribing antibiotic prophylaxis (AP). Many different protocols were observed, but the majority of dentists prescribe amoxicillin (2 g) 1 hour before a procedure. The greatest diversity was found in the prescriptions for post-procedure prophylaxis, but most professionals prescribe 500 mg of antibiotics every 8 hours for 7 days. An overwhelming 91.5% of participants think that guidelines for prescribing antibiotics in dentistry are necessary, and 62.2% believe that the use of AP can have some impact on bacterial resistance. There is a wide range of different prescriptions for antimicrobials, suggesting a need for better aligned guidelines and education of professionals on the proper use of antimicrobials and its consequences on bacterial resistance to antibiotics.
由于细菌耐药性的发展,抗菌药物的不合理使用已成为一个严重的流行病学问题,对全球健康造成了影响。在牙科领域,抗生素是第二大常用的药理学类别。因此,我们评估了巴西阿雷格里港和大都市区的牙医对抗菌药物预防使用的情况,采用了在线问卷调查的方式。要求牙医填写一份有关抗菌药物处方的匿名问卷。问卷是在 Microsoft Forms 平台上编写的,并通过社交媒体分发给牙医,为期 40 天。共有 82 名牙医回答了问卷,其中 85.3%的人报告使用了抗生素预防用药(AP)。我们观察到了许多不同的方案,但大多数牙医在手术前 1 小时开阿莫西林(2 克)。术后预防用药的处方差异最大,但大多数医生开 500 毫克抗生素,每 8 小时一次,连用 7 天。91.5%的参与者认为牙医需要制定抗生素使用指南,62.2%的人认为 AP 的使用可能对抗菌药物耐药性产生一定影响。抗菌药物的处方差异很大,这表明需要更好地协调指南,并对专业人员进行有关正确使用抗菌药物及其对抗菌药物耐药性影响的教育。