Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-Sen University, 74 Zhongshan Rd 2, Guangzhou, 510080, China.
Mood Disorders Psychopharmacology Unit, University Health Network, Toronto, ON, Canada.
BMC Psychiatry. 2023 Mar 20;23(1):179. doi: 10.1186/s12888-023-04654-7.
Depression among adolescents is a seriously disabling public health problem with an extremely high prevalence. Identifying risk factors of depression at an early stage is important to reduce the disease burden. Childhood maltreatment (CM) is one of the major risk factors for depression. The key mediating processes that how CM affects the development of depression, however, still need further clarification. The present study tested the mediating effect of self-esteem, internalizing problems, and externalizing problems between CM and depressive symptoms. Potential sex differences in the foregoing associations were also explored.
A three-wave longitudinal study was carried out among 1,957 middle and high school students from 69 classes in 10 public schools in the Guangdong province of China. Data collection started when students were in grades 7 and 10 (median age: 13.0, range: 11-18) between January and April 2019, and the students were followed up once a year thereafter. Self-reported CM, depressive symptoms, self-esteem, internalizing and externalizing problems, and other demographics were collected. The multiple serial mediation analysis was conducted.
We found that CM was positively related to subsequent internalizing and externalizing problems, as well as depressive symptoms, while self-esteem was negatively related to depressive symptoms. Serial mediation analysis indicated that self-esteem (mediator 1) and internalizing problems (mediator 2) sequentially mediated the path from CM to depressive symptoms in the overall and male population. Moreover, with externalizing problems as mediator 2, self-esteem (mediator 1) acted as a partial mediator in the association between CM and depressive symptoms in males, whereas externalizing problems played a complete mediating role in females.
Findings revealed that self-esteem and internalizing problems sequentially mediated the influence of CM on depressive symptoms whereas externalizing problems played an independent mediating role. In addition, sex differences need to be taken into consideration when designing prevention and intervention strategies, given the different psychosocial processes between boys and girls.
青少年抑郁是一种严重致残的公共卫生问题,其患病率极高。早期识别抑郁的风险因素对于减轻疾病负担非常重要。儿童期虐待(CM)是抑郁的主要危险因素之一。然而,CM 如何影响抑郁的发展的关键中介过程仍需进一步阐明。本研究测试了自尊、内化问题和外化问题在 CM 与抑郁症状之间的中介作用。还探讨了上述关联中的潜在性别差异。
在中国广东省 10 所公立学校的 69 个班级中,对 1957 名中学生进行了为期三年的纵向研究。数据收集始于学生在 7 年级和 10 年级(中位数年龄:13.0,范围:11-18)时,在 2019 年 1 月至 4 月期间,此后每年进行一次随访。收集了自我报告的 CM、抑郁症状、自尊、内化和外化问题以及其他人口统计学数据。进行了多次串行中介分析。
我们发现,CM 与随后的内化和外化问题以及抑郁症状呈正相关,而自尊与抑郁症状呈负相关。序列中介分析表明,在总体人群和男性人群中,自尊(中介 1)和内化问题(中介 2)依次介导了 CM 与抑郁症状之间的关系。此外,以外化问题作为中介 2,自尊(中介 1)在男性 CM 与抑郁症状的关联中起到部分中介作用,而在外化问题在女性中起完全中介作用。
研究结果表明,自尊和内化问题依次介导了 CM 对抑郁症状的影响,而外化问题则起到独立的中介作用。此外,鉴于男孩和女孩之间存在不同的心理社会过程,在设计预防和干预策略时需要考虑性别差异。