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乳鼠脑制备的狂犬病疫苗接种后吉兰-巴雷综合征的异常特征

Unusual features of the Guillain-Barré syndrome after rabies vaccine prepared in suckling mouse brain.

作者信息

Cabrera J, Griffin D E, Johnson R T

机构信息

Department of Neurology, Universidad Peruana Cayetano Heredia, Lima.

出版信息

J Neurol Sci. 1987 Nov;81(2-3):239-45. doi: 10.1016/0022-510x(87)90099-2.

Abstract

Five patients with acute polyneuritis following treatment with rabies vaccine prepared in suckling mouse brains are reported. These patients had severe and protracted disease. The extensive cranial nerve involvement, high mortality rate, and disabling longterm sequelae were in contrast to cases of the Guillain-Barré syndrome not associated with the vaccine.

摘要

报告了5例在接受乳鼠脑制备的狂犬病疫苗治疗后发生急性多发性神经炎的患者。这些患者患有严重且迁延不愈的疾病。广泛的颅神经受累、高死亡率以及导致残疾的长期后遗症与未接种该疫苗的格林-巴利综合征病例形成对比。

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