Kang Danbee, Kim Nayeon, Han Gayeon, Kim Sooyeon, Kim Hoyoung, Lim Jihyun, Kim Hyunsoo, Shim Sungkeun, Lee Mangyeong, Lee Jeong Eon, Nam Seok Jin, Kim Seok Won, Yu Jonghan, Lee Se Kyung, Cho Juhee
Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, Seoul, South Korea.
Center for Clinical Epidemiology, Samsung Medical Center, Sungkyunkwan University, Seoul, South Korea.
Palliat Support Care. 2022 Dec;20(6):807-812. doi: 10.1017/S1478951521001711.
This study aims to identify factors associated with divorce following breast cancer diagnosis and measures the impact of divorce on the quality of life (QoL) of patients.
We used cross-sectional survey data collected at breast cancer outpatient clinics in South Korea from November 2018 to April 2019. Adult breast cancer survivors who completed active treatment without any cancer recurrence at the time of the survey ( = 4,366) were included. The participants were classified into two groups: "maintaining marriage" and "being divorced," between at the survey and at the cancer diagnosis. We performed logistic regression and linear regression to identify the factors associated with divorce after cancer diagnosis and to compare the QoL of divorced and nondivorced survivors.
Approximately 11.1/1,000 of married breast cancer survivors experienced divorce after cancer diagnosis. Younger age, lower education, and being employed at diagnosis were associated with divorce. Being divorced survivors had significantly lower QoL (Coefficient [Coef] = -7.50; 95% CI = -13.63, -1.36), social functioning (Coef = -9.47; 95% CI = -16.36, -2.57), and body image (Coef = -8.34; 95% CI = -6.29, -0.39) than survivors who remained married. They also experienced more symptoms including pain, insomnia, financial difficulties, and distress due to hair loss.
Identifying risk factors of divorce will ultimately help ascertain the resources necessary for early intervention.
本研究旨在确定乳腺癌诊断后与离婚相关的因素,并衡量离婚对患者生活质量(QoL)的影响。
我们使用了2018年11月至2019年4月在韩国乳腺癌门诊收集的横断面调查数据。纳入了在调查时已完成积极治疗且无任何癌症复发的成年乳腺癌幸存者(n = 4366)。参与者被分为两组:在调查时和癌症诊断时处于“维持婚姻”和“已离婚”状态。我们进行了逻辑回归和线性回归,以确定癌症诊断后与离婚相关的因素,并比较离婚和未离婚幸存者的生活质量。
大约每1000名已婚乳腺癌幸存者中有11.1人在癌症诊断后经历离婚。年龄较小、教育程度较低以及诊断时就业与离婚有关。与仍维持婚姻的幸存者相比,已离婚的幸存者的生活质量(系数[Coef] = -7.50;95%置信区间[CI] = -13.63,-1.36)、社会功能(Coef = -9.47;95% CI = -16.36,-2.57)和身体形象(Coef = -8.34;95% CI = -6.29,-0.39)显著较低。他们还经历了更多症状,包括疼痛、失眠、经济困难和因脱发而产生的困扰。
识别离婚的风险因素最终将有助于确定早期干预所需的资源。