Walczak Dominik, Sikorski Artur, Grzywacz Daria, Nowacki Andrzej, Liberek Beata
Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308, Gdańsk, Poland.
Faculty of Chemistry, University of Gdańsk, Wita Stwosza 63, 80-308, Gdańsk, Poland.
Carbohydr Res. 2023 Apr;526:108780. doi: 10.1016/j.carres.2023.108780. Epub 2023 Mar 3.
Three groups of furanoses with restricted freedom of rotation on the C3-C4, C2-C3, and C1-C2 bonds, respectively, are presented. Conformational analysis of these furanoses is conducted based on the proton nuclear magnetic resonance (H NMR) spectroscopy, density functional theory (DFT) calculations, and X-ray analysis. It is shown that the particular group of the presented furanoses is locked in the specific conformation. These are the T-like, the E-like, and the T-like conformation, respectively. Characteristic H NMR spectra of these three conformations are presented and the factors influencing the conformational preferences of the analyzed furanoses are discussed.
分别展示了三组在C3-C4、C2-C3和C1-C2键上旋转自由度受限的呋喃糖。基于质子核磁共振（H NMR）光谱、密度泛函理论（DFT）计算和X射线分析对这些呋喃糖进行了构象分析。结果表明，所展示的特定组呋喃糖被锁定在特定构象中。它们分别是T型、E型和T型构象。给出了这三种构象的特征H NMR光谱，并讨论了影响所分析呋喃糖构象偏好的因素。
