[Pharmacological studies on antihepatotoxic action of (+)-(6S,7S,R-biar)-5,6,7,8-tetrahydro-1,2,3,12-tetramethoxy++ + -6,7-dimethyl-10,11-methylenedioxy-6-dibenzo[a,c] cyclooctenol (TJN-101), a lignan component of Schisandra fruits. Influences of resolvents on the efficacy of TJN-101 in the experimental acute hepatic injuries].
作者信息
Takeda S, Arai I, Kase Y, Ohkura Y, Hasegawa M, Sekiguchi Y, Sudo K, Aburada M, Hosoya E
出版信息
Yakugaku Zasshi. 1987 Jul;107(7):517-24. doi: 10.1248/yakushi1947.107.7_517.
PMID:3694461
Abstract
摘要
相似文献
1
[Pharmacological studies on antihepatotoxic action of (+)-(6S,7S,R-biar)-5,6,7,8-tetrahydro-1,2,3,12-tetramethoxy++ + -6,7-dimethyl-10,11-methylenedioxy-6-dibenzo[a,c] cyclooctenol (TJN-101), a lignan component of Schisandra fruits. Influences of resolvents on the efficacy of TJN-101 in the experimental acute hepatic injuries].五味子果实木脂素成分（+）-（6S，7S，R-biar）-5，6，7，8-四氢-1，2，3，12-四甲氧基-6，7-二甲基-10，11-亚甲二氧基-6-二苯并[a，c]环辛烯醇（TJN-101）抗肝毒性作用的药理学研究。溶剂对TJN-101在实验性急性肝损伤中疗效的影响
Yakugaku Zasshi. 1987 Jul;107(7):517-24. doi: 10.1248/yakushi1947.107.7_517.
2
[Effects of TJN-101, a lignan compound isolated from Schisandra fruits, on liver fibrosis and on liver regeneration after partial hepatectomy in rats with chronic liver injury induced by CCl4].[从五味子果实中分离出的木脂素化合物TJN-101对四氯化碳诱导的慢性肝损伤大鼠肝纤维化及部分肝切除术后肝脏再生的影响]
Nihon Yakurigaku Zasshi. 1987 Jul;90(1):51-65. doi: 10.1254/fpj.90.51.
3
Inhibitory effect of TJN-101 ((+)-(6S,7S,R-biar)-5,6,7,8-tetrahydro-1,2,3,12-tetramethoxy -6,7-dimethyl-10,11- methylenedioxy-6-dibenzo[a,c]cyclooctenol) on immunologically induced liver injuries.TJN-101（(+)-(6S,7S,R-biar)-5,6,7,8-四氢-1,2,3,12-四甲氧基-6,7-二甲基-10,11-亚甲基二氧基-6-二苯并[a,c]环辛烯醇）对免疫诱导性肝损伤的抑制作用
Jpn J Pharmacol. 1987 Jun;44(2):179-85. doi: 10.1254/jjp.44.179.
4
[Effect of gomisin A (TJN-101), a lignan compound isolated from Schisandra fruits, on liver function in rats].[五味子果实中分离出的木脂素化合物戈米辛A（TJN - 101）对大鼠肝功能的影响]
Nihon Yakurigaku Zasshi. 1988 Apr;91(4):237-44. doi: 10.1254/fpj.91.237.
5
[Effects of TJN-101 ((+)-(6s,7s,R-biar)-5,6,7,8-tetrahydro-1,2,3,12-tetramethoxy-6,7 -dimethyl-10,11-methylenedioxy-6-dibenzo [a,c] cyclooctenol) on liver regeneration after partial hepatectomy, and on regional hepatic blood flow and fine structure of the liver in normal rats].TJN-101（(+)-(6s,7s,R-biar)-5,6,7,8-四氢-1,2,3,12-四甲氧基-6,7-二甲基-10,11-亚甲基二氧基-6-二苯并[a,c]环辛烯醇）对部分肝切除术后肝脏再生、正常大鼠肝脏局部血流及肝脏细微结构的影响
Nihon Yakurigaku Zasshi. 1986 Oct;88(4):321-30. doi: 10.1254/fpj.88.321.
6
Occurrence of autoimmune antibodies to liver microsomal proteins associated with lethal hepatitis in LEC rats: effects of TJN-101 ((+)-(6S,7S,R-biar)- 5,6,7,8-tetrahydro-1,2,3,12-tetramethoxy-6,7-dimethyl-10,11- methylenedioxy-6-dibenzo[a,c]cyclooctenol) on the development of hepatitis and the autoantibodies.与LEC大鼠致死性肝炎相关的肝脏微粒体蛋白自身抗体的出现：TJN-101（(+)-(6S,7S,R-biar)-5,6,7,8-四氢-1,2,3,12-四甲氧基-6,7-二甲基-10,11-亚甲基二氧基-6-二苯并[a,c]环辛烯醇）对肝炎及自身抗体产生的影响
Toxicol Lett. 1995 Feb;76(1):33-8. doi: 10.1016/0378-4274(94)03190-8.
7
Effect of gomisin A (TJN-101) on the arachidonic acid cascade in macrophages.五味子素A（TJN - 101）对巨噬细胞中花生四烯酸级联反应的影响。
Jpn J Pharmacol. 1990 Feb;52(2):331-6. doi: 10.1254/jjp.52.331.
8
Effect of Gomisin A (TJN-101) on liver regeneration.五味子甲素（TJN-101）对肝脏再生的影响。
Planta Med. 1992 Dec;58(6):489-92. doi: 10.1055/s-2006-961532.
9
[Pharmacological studies on schizandra fruits. II. Effects of constituents of shizandra fruits on drugs induced hepatic damage in rats].
Yakugaku Zasshi. 1982 Jun;102(6):579-88. doi: 10.1248/yakushi1947.102.6_579.
10
Mechanism of antihepatotoxic activity of wuweizisu C and gomisin A.
Planta Med. 1985 Aug(4):331-4.
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