Department of Pathology & Lab Medicine, AIIMS, Kalyani, India.
Department of Dermatology, AIIMS, Mangalagiri, India.
BMC Womens Health. 2023 Mar 21;23(1):118. doi: 10.1186/s12905-023-02280-9.
Granulomatous cheilitis (GC) is a rare entity of unknown etiology. It is a chronic inflammatory disorder with a predilection for young females. It is characterized by asymptomatic unrelenting swelling of lips. It is a monosymptomatic form or an incomplete variant of Melkersson-Rosenthal syndrome (a triad of recurrent orofacial swelling, relapsing facial paralysis, and fissuring of the tongue).
We herewith report a case of a 27-year-old female, presenting with persistent upper lip swelling, for 3 months. Biopsy from the lesion revealed features of granulomatous cheilitis.
GC should be considered in the differential diagnosis of unrelenting swelling in the lip. Spontaneous remission is rare, and recurrences are common. Corticosteroids used for treatment provide temporary improvement.
肉芽肿性唇炎（GC）是一种病因不明的罕见疾病。它是一种慢性炎症性疾病，好发于年轻女性。其特征是无症状的持续唇部肿胀。它是梅克尔逊-罗森塔尔综合征（复发性口腔肿胀、复发性面瘫和舌裂三联征）的一种单症状形式或不完整变异。
我们在此报告一例 27 岁女性，持续性上唇肿胀 3 个月。病变活检显示肉芽肿性唇炎的特征。
GC 应在唇部持续性肿胀的鉴别诊断中考虑。自发缓解罕见，复发常见。皮质类固醇用于治疗可提供暂时改善。
