血管内皮生长因子（VEGF）与番茄化合物的分子对接分析。
Molecular docking analysis of VEGF with compounds from tomato.
作者信息
Krishnan Madhan, Babu Shyamaladevi, Thomas Suni Ann, Surulivel Jaya Senthilnathan, Ayyanar Kavitha
机构信息
Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, chengalpattu District, Tamilnadu, India.
Department of Biochemistry, Al Azhar Medical College Thodupuzha, Kumaramangalam, Kerala, India.
出版信息
Bioinformation. 2022 May 31;18(5):478-481. doi: 10.6026/97320630018478. eCollection 2022.
Abstract
Vascular endothelial growth factor (VEGF) is linked with Non-small cell lung carcinoma (NSCLC). Therefore it is of interest to document data on the molecular docking analysis of VEGF with compounds from tomato for consideration drug discovery. Data shows that compounds Kaempferol-3-O, Quercetin, Naringenin & Rutin show optimal binding.
摘要
血管内皮生长因子（VEGF）与非小细胞肺癌（NSCLC）有关。因此，记录VEGF与番茄化合物的分子对接分析数据以用于药物发现是很有意义的。数据显示，化合物山奈酚-3-O、槲皮素、柚皮素和芦丁表现出最佳结合。
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