Bang Hyewon, Kim Nam-Hee, Choi Seung Hye, Bae Si Hyun, Jung Eun Sun, Min Ki Ouk, Eom Yong Hwa
Department of Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Korean J Clin Oncol. 2022 Dec;18(2):93-96. doi: 10.14216/kjco.22013. Epub 2022 Dec 30.
Breast metastases from extramammary malignancies are rare. Here, we report a case of breast metastasis from hepatocellular carcinoma (HCC) after breast mass excision in a 63-year-old woman. A new breast nodule was noticed after transarterial chemoembolization, transarterial radioembolization, and stereotactic body radiation therapy for HCC. Breast ultrasound and core needle biopsy were performed to differentiate between the breast tumors. The biopsy result was invasive breast carcinoma, and wide excision of the breast was performed. The final pathological diagnosis was HCC breast metastasis based on histological findings and immunohistochemical staining results. After 9 months of follow-up, HCC and breast metastasis recurred. Despite palliative treatment, the patient died due to complications and general health deterioration. Although breast metastasis due to HCC is very rare, HCC breast metastasis should be considered when a new breast mass is discovered in a patient with a history of HCC for effective treatment and management.
乳腺外恶性肿瘤的乳腺转移罕见。在此，我们报告一例63岁女性在乳腺肿块切除术后发生肝细胞癌（HCC）乳腺转移的病例。在对HCC进行经动脉化疗栓塞、经动脉放射性栓塞和立体定向体部放射治疗后，发现了一个新的乳腺结节。进行了乳腺超声和粗针活检以鉴别乳腺肿瘤。活检结果为浸润性乳腺癌，并进行了乳腺广泛切除术。根据组织学检查结果和免疫组化染色结果，最终病理诊断为HCC乳腺转移。随访9个月后，HCC和乳腺转移复发。尽管进行了姑息治疗，患者仍因并发症和全身健康状况恶化而死亡。虽然HCC导致的乳腺转移非常罕见，但对于有HCC病史的患者，当发现新的乳腺肿块时，应考虑HCC乳腺转移，以便进行有效的治疗和管理。
