Kim Seo Ree, Chun Sang Hoon, Jin Jong Youl, Gweon Tae-Geun, Lee Hayemin, Jin Min-Sun, Lee Guk Jin
Division of Hematology-Oncology, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Division of Gastroenterology, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Korean J Clin Oncol. 2021 Dec;17(2):126-130. doi: 10.14216/kjco.21020. Epub 2021 Dec 31.
There have been several reports of complications of small bowel lymphoma, such as bleeding, obstruction, and perforation, often require emergency surgery. It is hardly showed complications of bleeding and wound dehiscence for diffuse large B cell lymphoma with distal ileum involvement, which needed urgent surgery and medical management. A 65-year-old man with diffuse large B-cell lymphoma with distal ileum involvement experienced both intestinal bleeding and perforation during the course of treatment. As the patient was diagnosed with stage III disease, resection before chemotherapy was not considered due to the resulting delay in chemotherapy, which necessitated sufficient tissue healing. Chemotherapy is important when treating small bowel lymphoma, complications such as bleeding and perforation should always be considered for the treatment of small bowel lymphoma, and surgery is necessary in this situation. After surgery of the small bowel, subsequent chemotherapy could cause wound dehiscence and perforation; therefore, adequate recovery time should be given before chemotherapy.
已有多篇关于小肠淋巴瘤并发症的报道，如出血、梗阻和穿孔，这些情况常需要紧急手术。对于累及回肠末端的弥漫性大B细胞淋巴瘤，很少出现出血和伤口裂开等并发症，这种情况需要紧急手术和药物治疗。一名65岁的男性患者，患有累及回肠末端的弥漫性大B细胞淋巴瘤，在治疗过程中出现了肠道出血和穿孔。由于该患者被诊断为III期疾病，考虑到化疗会因此延迟，而化疗需要足够的组织愈合时间，所以未在化疗前进行切除手术。治疗小肠淋巴瘤时化疗很重要，治疗小肠淋巴瘤时应始终考虑出血和穿孔等并发症，在这种情况下手术是必要的。小肠手术后，后续化疗可能导致伤口裂开和穿孔；因此，化疗前应给予足够的恢复时间。
