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犬恶丝虫引起的肺部硬币状病变——两例报告并文献综述

Pulmonary coin lesion caused by Dirofilaria immitis - a report of two cases with a minireview of the literature.

作者信息

Jerše Maja

机构信息

Faculty of Medicine, Institute of Pathology, University of Ljubljana, Ljubljana, Slovenia.

出版信息

Pol J Pathol. 2022;73(4):352-358. doi: 10.5114/pjp.2022.125821.

DOI:10.5114/pjp.2022.125821
PMID:36946272
Abstract

Dirofilariasis is a rare zoonosis, transmitted from infested dogs or other carnivorous animals to humans via mosquitoes. Two male patients with a solitary, peripheral, well-defined, coin-like pulmonary lesion in the right upper lobe were presented. Rapid enlargement of the lesion within a few months suggested malignancy, resulting in surgical removal. Microscopic examination of the resected lung revealed necrotic circumscribed lesions with embolized parasites in the vessels. Both parasites were females of the species Dirofilaria immitis. They represent the first reported cases of pulmonary dirofilariasis in Slovenia. Awareness of this entity is important in the differential diagnosis of pulmonary coin lesions.

摘要

犬恶丝虫病是一种罕见的人畜共患病,通过蚊子从受感染的狗或其他食肉动物传播给人类。本文报告了两名男性患者,右上叶有一个孤立的、外周清晰的硬币状肺部病变。病变在几个月内迅速增大提示恶性肿瘤,因此进行了手术切除。对切除的肺组织进行显微镜检查,发现有坏死的局限性病变,血管内有寄生虫栓塞。两条寄生虫均为犬恶丝虫雌性成虫。它们是斯洛文尼亚首次报告的肺犬恶丝虫病病例。认识到这一疾病实体对于肺部硬币状病变的鉴别诊断很重要。

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