Rodrigues Anaïs, Delhomme Olivier, Millet Maurice
Institute of Chemistry and Processes for Energy, Environment and Health (UMR 7515 CNRS), University of Strasbourg, 25 rue Becquerel, F-67087 Strasbourg Cedex, France.
University of Lorraine, F-57000 Metz, France.
J Chromatogr Sci. 2024 Mar 23;62(3):257-263. doi: 10.1093/chromsci/bmad020.
An analytical method coupling pressurized liquid extraction (PLE), pre-concentration by thermal desorption (ATD) and analysis by GC/MSMS was developed for the quantification of pesticides in air and dust near vineyards crops to evaluate potential exposure of residents living near these crops. PLE was done using acetonitrile and extracts were concentrated under fume hood to 1 mL. 100 μL of the extract was spiked in a Tenax TA tube and internal standards and N-tert-butyldimethylsilyl-N-methyltrifluoroacetamide were added before thermal desorption at 300°C for 30 min. GC/MSMS analysis was done in MRM mode and limits of quantification and limits of detection were determined for each matrix (passive air sample, active air sample and dust). The method was applied in the field and shows good sensitivity and accuracy.
建立了一种将加压液体萃取（PLE）、热脱附预浓缩（ATD）和气相色谱/串联质谱分析相结合的分析方法，用于定量葡萄园作物附近空气和灰尘中的农药，以评估居住在这些作物附近居民的潜在暴露情况。采用乙腈进行PLE，提取物在通风橱中浓缩至1 mL。取100 μL提取物加入Tenax TA管中，加入内标和N-叔丁基二甲基硅基-N-甲基三氟乙酰胺，然后在300℃下热脱附30分钟。气相色谱/串联质谱分析采用多反应监测（MRM）模式，测定了每种基质（被动空气样品、主动空气样品和灰尘）的定量限和检测限。该方法应用于现场，具有良好的灵敏度和准确性。
