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早期阿尔茨海默病的诊断与治疗。

Diagnosing and Treating Alzheimer Disease During the Early Stage.

机构信息

Barrow Neurological Institute, Phoenix, Arizona.

Banner Sun Health Research Institute, Sun City, Arizona.

出版信息

J Clin Psychiatry. 2023 Mar 22;84(2):LI21019AH3C. doi: 10.4088/JCP.LI21019AH3C.

Abstract

Recent advances in technology can lead to earlier detection of Alzheimer disease (AD) in patients and therefore opportunities for early diagnosis and treatment. In addition, novel agents can slow disease progression and improve symptoms. However, clinicians are not providing a diagnosis to over half of individuals who meet criteria for dementia. Early detection and intervention are crucial to slow symptom progression, and these advances provide a window of opportunity to diagnose the disease early and even prevent it from becoming symptomatic. Clinicians need education on early recognition of AD and on sharing the diagnosis of AD with patients and families as well as guidance for providing patients and families with information on next steps and facilitating early treatment initiation for AD. Partnering with clinicians in the primary care setting and providing them with the necessary tools can change the trajectory of the disease for patients and caregivers.

摘要

技术的最新进展可以帮助更早地发现阿尔茨海默病(AD)患者,从而为早期诊断和治疗提供机会。此外,新型药物可以减缓疾病进展并改善症状。然而,临床医生并未对超过一半符合痴呆症标准的患者做出诊断。早期发现和干预对于减缓症状进展至关重要,这些进展为早期诊断疾病甚至预防其出现症状提供了机会。临床医生需要接受有关早期识别 AD 和与患者及家属分享 AD 诊断的教育,以及为患者和家属提供下一步信息和促进早期 AD 治疗的指导。与初级保健环境中的临床医生合作并为他们提供必要的工具,可以改变患者和护理人员的疾病轨迹。

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