Krawiec Maciej, Dominiak Marzena
Department of Oral Surgery, Wroclaw Medical University, Poland.
Dent Med Probl. 2021 Jul-Sep;58(3):321-326. doi: 10.17219/dmp/134911.
The available epidemiological data indicates the existence of numerous tooth deficiencies and periodontopathies in the Polish population. Successful surgical treatment is dependent upon multiple factors, including bone quality, which is affected by vitamin D - one of the regulators of calcium (Ca) and phosphorus (P) metabolism.
The aim of this study was to conduct a prospective evaluation of the levels of vitamin D among patients receiving dental treatment for various reasons (conservative, surgical or prosthodontic treatment).
The study involved 60 patients, who, for various reasons, were admitted for dental treatment for over a 1-week period in the summer season. A thorough interview together with a periodontological examination consisting of probing depth (PD) and clinical attachment level (CAL) measurements, were conducted. A total of 2 mL of blood was collected from each patient to determine the concentrations of vitamin D, parathyroid hormone (PTH), Ca, magnesium (Mg), and P in the blood with the use of mass spectrometry.
Among the 60 patients enrolled in the study, 53 (88.3%) showed vitamin D deficiency and 18 (30%) showed a concentration below 17.8 ng/mL, which is an independent general mortality factor. The difference in the level of vitamin D between group A (without periodontitis) and group B (with periodontitis) was not statistically significant (p = 0.076), but a tendency for lower vitamin D levels in people with periodontitis was observed. We also observed a tendency for periodontal disease to occur more often with extreme vitamin D deficiency (<15 ng/mL) (p = 0.730).
Low levels of vitamin D are present in a large proportion of dental patients, and an increase in the incidence of periodontal disease is likely associated with a decrease in the level of vitamin D.
现有流行病学数据表明波兰人群中存在大量牙齿缺陷和牙周疾病。成功的外科治疗取决于多种因素，包括骨质，而骨质会受到维生素D的影响，维生素D是钙（Ca）和磷（P）代谢的调节因子之一。
本研究的目的是对因各种原因接受牙科治疗（保守治疗、外科治疗或修复治疗）的患者的维生素D水平进行前瞻性评估。
该研究纳入了60名患者，这些患者在夏季因各种原因接受了为期1周以上的牙科治疗。进行了全面的访谈以及包括探诊深度（PD）和临床附着水平（CAL）测量的牙周检查。从每位患者采集2 mL血液，使用质谱法测定血液中维生素D、甲状旁腺激素（PTH）、钙、镁（Mg）和磷的浓度。
在纳入研究的60名患者中，53名（88.3%）存在维生素D缺乏，18名（30%）的维生素D浓度低于17.8 ng/mL，这是一个独立的总体死亡因素。A组（无牙周炎）和B组（有牙周炎）之间的维生素D水平差异无统计学意义（p = 0.076），但观察到牙周炎患者的维生素D水平有降低的趋势。我们还观察到，维生素D极度缺乏（<15 ng/mL）的人群中牙周疾病的发生率更高（p = 0.730）。
大部分牙科患者的维生素D水平较低，牙周疾病发病率的增加可能与维生素D水平的降低有关。
