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莱格尼察-格沃古夫铜矿区患者阻生智齿中的汞含量——一项体外初步研究

Mercury Content in Impacted Wisdom Teeth from Patients of the Legnica-Głogów Copper Area-An In Vitro Pilot Study.

作者信息

Rayad Sadri, Dobrzyński Maciej, Kuźniarski Amadeusz, Styczyńska Marzena, Diakowska Dorota, Gedrange Tomasz, Klimas Sylwia, Gębarowski Tomasz, Dominiak Marzena

机构信息

Academic Dental Polyclinic of Dental Center, Technology Transfer Ltd., Krakowska 26, 50-425 Wroclaw, Poland.

Department of Pediatric Dentistry and Preclinical Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.

出版信息

J Xenobiot. 2023 Aug 27;13(3):463-478. doi: 10.3390/jox13030029.

Abstract

The aim of this study was to determine the content of mercury in impacted third molars from Legnica-Głogów Copper Area residents to emphasize the effects of environmental pollution on the human body. A group of 72 patients with an average age of 27.3 ± 6.9 years participated in the study. Within this study, the research group (Legnica-Głogów Copper Area residents) comprised 51 individuals, while the control group (residents of Wrocław) consisted of 21 participants. A higher number of female individuals participated in the research (55). The amount of mercury present in the samples was determined through atomic absorption spectrometry with the use of a SpectraAA atomic absorption spectrometer and a V2 AA240FS flame attachment that utilized an air-acetylene flame. The accumulation of Hg in the teeth of members of the control group residing in Wrocław was studied, with a focus on identifying the risk factors that contribute to this phenomenon. The final model analyzed the presence of various factors, including thyroid and parathyroid gland diseases, cardiac diseases, and interval-scale Vit. D3 concentration. Among these factors, the presence of cardiac diseases was deemed statistically significant in relation to an increase in Hg concentration in third molars (rate ratio = 2.27, < 0.0001). The concentration of mercury increased with the age and time of residence in the L-G Copper District.

摘要

本研究的目的是测定莱格尼察-格沃古夫铜矿区居民阻生第三磨牙中的汞含量,以强调环境污染对人体的影响。一组平均年龄为27.3±6.9岁的72名患者参与了该研究。在本研究中,研究组(莱格尼察-格沃古夫铜矿区居民)包括51人,而对照组(弗罗茨瓦夫居民)由21名参与者组成。参与研究的女性个体数量较多(55人)。通过使用SpectraAA原子吸收光谱仪和配备空气-乙炔火焰的V2 AA240FS火焰附件的原子吸收光谱法测定样品中的汞含量。研究了居住在弗罗茨瓦夫的对照组成员牙齿中汞的积累情况,重点是确定导致这种现象的风险因素。最终模型分析了各种因素的存在情况,包括甲状腺和甲状旁腺疾病、心脏病以及间隔尺度的维生素D3浓度。在这些因素中,心脏病的存在被认为与第三磨牙中汞浓度的增加在统计学上具有显著相关性(率比=2.27,<0.0001)。汞浓度随着在L-G铜矿区的年龄和居住时间的增加而升高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93b9/10532917/753765801c5b/jox-13-00029-g001.jpg

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