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黏膜皮肤皮下丛皮瓣在犬完全切除恶性皮肤和结膜黑素瘤中的应用。

Mucocutaneous subdermal plexus flap for complete excision of a malignant dermal and conjunctival melanoma in a dog.

机构信息

Eye Care for Animals, Pasadena, California, USA.

Antech Diagnostics, Fountain Valley, California, USA.

出版信息

Vet Ophthalmol. 2023 May;26(3):243-249. doi: 10.1111/vop.13064. Epub 2023 Mar 22.

Abstract

PURPOSE

To perform a reconstructive blepharoplasty to obtain complete surgical excision of a darkly pigmented raised conjunctival-eyelid mass of the lower eyelid in a dog.

ANIMAL STUDIED

A 7-year-old, female-spayed, Yorkshire Terrier was evaluated for a slowly progressive, dark brown-to-black raised mass of the lower left eyelid. Sampling of the mass via fine-needle aspirate or incisional biopsy was declined, and an excision of the mass with the goal to obtain complete margins and maintain normal eyelid function with cosmesis was elected.

PROCEDURES

The lower palpebral conjunctival-eyelid pigmented mass was excised en bloc and the lower eyelid was reconstructed with a mucocutaneous subdermal plexus flap.

RESULTS

Histopathology revealed a malignant dermal and conjunctivalmelanoma excised with complete margins (1-2 mm). Short-term complications included corneal ulceration and eschar formation, which resolved completely at the 1-month follow-up. Long-term complications included mild trichiasis with epiphora and porphyrin staining. Tumor recurrence was not observed during an 8-month follow-up period.

CONCLUSIONS

The en bloc excision with mucocutaneous subdermal plexus flap was successful in obtaining complete surgical margins for a malignant conjunctival-eyelid melanoma. An excellent functional and cosmetic outcome was achieved without tumor recurrence during an 8-month follow-up period. A mucocutaneous subdermal plexus flap can be considered as a surgical option for malignant melanoma of the lower eyelid.

摘要

目的

对一只狗的下眼睑进行重建性眼睑成形术,以彻底切除深色、隆起的结膜-眼睑色素性肿块。

研究动物

一只 7 岁、雌性去势的约克夏梗犬因左下眼睑出现逐渐进展的深棕色至黑色隆起肿块而接受评估。肿块的细针抽吸或切开活检被拒绝,选择切除肿块,目标是获得完整的切缘,并保持正常的眼睑功能和美容效果。

手术过程

整块切除下眼睑结膜-眼睑色素性肿块,并采用黏膜皮下丛状皮瓣重建下眼睑。

结果

组织病理学显示切除的恶性真皮和结膜黑色素瘤有完整的切缘(1-2mm)。短期并发症包括角膜溃疡和焦痂形成,在 1 个月的随访时完全缓解。长期并发症包括轻度倒睫伴溢泪和卟啉染色。在 8 个月的随访期间未观察到肿瘤复发。

结论

整块切除联合黏膜皮下丛状皮瓣成功获得恶性结膜-眼睑黑色素瘤的完整手术切缘。在 8 个月的随访期间,无肿瘤复发,实现了极佳的功能和美容效果。黏膜皮下丛状皮瓣可被视为下眼睑恶性黑色素瘤的一种手术选择。

相似文献

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Management of eyelid neoplasms in the dog and cat.犬猫眼睑肿瘤的管理
Clin Tech Small Anim Pract. 2007 May;22(2):46-54. doi: 10.1053/j.ctsap.2007.03.001.
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Malignant melanoma of the eyelid and conjunctiva.眼睑及结膜恶性黑色素瘤
Aust N Z J Ophthalmol. 1986 Feb;14(1):29-34. doi: 10.1111/j.1442-9071.1986.tb00004.x.

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