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1
Darolutamide Plus Androgen-Deprivation Therapy and Docetaxel in Metastatic Hormone-Sensitive Prostate Cancer by Disease Volume and Risk Subgroups in the Phase III ARASENS Trial.在 III 期 ARASENS 试验中，根据疾病体积和风险亚组，达罗他胺联合雄激素剥夺治疗和多西他赛治疗转移性激素敏感性前列腺癌。
J Clin Oncol. 2023 Jul 10;41(20):3595-3607. doi: 10.1200/JCO.23.00041. Epub 2023 Feb 16.
2
Treatment Intensification Patterns and Utilization in Patients with Metastatic Castration-Sensitive Prostate Cancer.转移性去势敏感型前列腺癌患者的强化治疗模式和利用情况。
Clin Genitourin Cancer. 2022 Dec;20(6):524-532. doi: 10.1016/j.clgc.2022.06.017. Epub 2022 Jun 28.
3
Improved Survival With Enzalutamide in Patients With Metastatic Hormone-Sensitive Prostate Cancer.恩杂鲁胺可改善转移性去势敏感性前列腺癌患者的生存。
J Clin Oncol. 2022 May 20;40(15):1616-1622. doi: 10.1200/JCO.22.00193. Epub 2022 Apr 14.
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Abiraterone plus prednisone added to androgen deprivation therapy and docetaxel in de novo metastatic castration-sensitive prostate cancer (PEACE-1): a multicentre, open-label, randomised, phase 3 study with a 2 × 2 factorial design.阿比特龙联合泼尼松加至去势治疗和多西他赛用于初治转移性去势敏感性前列腺癌（PEACE-1）：一项采用2×2析因设计的多中心、开放标签、随机3期研究。
Lancet. 2022 Apr 30;399(10336):1695-1707. doi: 10.1016/S0140-6736(22)00367-1. Epub 2022 Apr 8.
5
Darolutamide and Survival in Metastatic, Hormone-Sensitive Prostate Cancer.达罗他胺与转移性去势敏感性前列腺癌的生存 **注**：这是基于你提供的文本进行的翻译，实际翻译可能会因上下文和语言习惯而有所不同。
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Overall Survival of Men with Metachronous Metastatic Hormone-sensitive Prostate Cancer Treated with Enzalutamide and Androgen Deprivation Therapy.转移性去势敏感性前列腺癌患者接受恩杂鲁胺和雄激素剥夺治疗的总生存情况。
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Apalutamide in Patients With Metastatic Castration-Sensitive Prostate Cancer: Final Survival Analysis of the Randomized, Double-Blind, Phase III TITAN Study.阿帕鲁胺治疗转移性去势敏感性前列腺癌患者的生存分析：随机、双盲、III 期 TITAN 研究的最终生存分析。
J Clin Oncol. 2021 Jul 10;39(20):2294-2303. doi: 10.1200/JCO.20.03488. Epub 2021 Apr 29.
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Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer.恩扎卢胺联合标准一线治疗转移性前列腺癌。
N Engl J Med. 2019 Jul 11;381(2):121-131. doi: 10.1056/NEJMoa1903835. Epub 2019 Jun 2.
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Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial.醋酸阿比特龙联合泼尼松治疗新诊断的高危转移性去势敏感性前列腺癌（LATITUDE）：一项随机、双盲、III 期临床试验的最终总生存分析。
Lancet Oncol. 2019 May;20(5):686-700. doi: 10.1016/S1470-2045(19)30082-8. Epub 2019 Apr 12.
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Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial.新诊断转移性前列腺癌原发肿瘤放疗（STAMPEDE）：一项随机对照 3 期试验。
Lancet. 2018 Dec 1;392(10162):2353-2366. doi: 10.1016/S0140-6736(18)32486-3. Epub 2018 Oct 21.

The Past, Present, and Future of Treatment Intensification for Metastatic Hormone-Sensitive Prostate Cancer.

作者信息

McManus Hannah D, Armstrong Andrew J

机构信息

Department of Medicine, Duke Cancer Institute Center for Prostate and Urologic Cancers, Duke University, Durham, NC.

出版信息

J Clin Oncol. 2023 Jul 10;41(20):3576-3579. doi: 10.1200/JCO.23.00323. Epub 2023 Mar 22.

DOI:10.1200/JCO.23.00323
PMID:36947730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10325746/
Abstract
摘要