Okawa T, Kita M, Goto M
Dept. of Radiology, Tokyo Women's Medical College.
Gan No Rinsho. 1987 Oct;33(13):1527-31.
The purpose of this paper is to report the clinical analysis and radiation strategy for cancer in the therapeutic ratio (T.R.) which were decided on relationship between tumor lethal dose and tissue tolerance. T.R. was first described at 1936, 40 years after discovering X-ray, by Holthusen. It is the basic principle of Radiotherapy for Radiation Oncologist. Radiotherapy must be planned on basing T.R. which is decided after estimating tumor factor, normal tissue tolerance, and host condition. In recent years, not only early skin reaction but late deep organs effects should be considered on T.R. because radiation energy has become higher from KeV era to MeV. The Optimum radiation methods has been investigated according to consider T.R.
本文旨在报告基于肿瘤致死剂量与组织耐受性之间关系所确定的治疗比（T.R.）的癌症临床分析及放疗策略。T.R. 于1936年被霍尔图森首次描述，这是在发现X射线40年后。它是放射肿瘤学家进行放射治疗的基本原则。放疗必须基于治疗比来规划，而治疗比是在评估肿瘤因素、正常组织耐受性和宿主状况后确定的。近年来，由于辐射能量从千电子伏特时代发展到兆电子伏特时代，治疗比不仅要考虑早期皮肤反应，还要考虑晚期深部器官效应。根据治疗比进行了最佳放疗方法的研究。
