Jingu K, Hayabuchi N, Matsui M, Wada S, Miyoshi M, Uehara S, Shimamura Y, Hirata H, Ariji E, Moriguchi S
Dept. of Radiology, Faculty of Med., Kyusyu Univ.
Gan No Rinsho. 1987 Oct;33(13):1609-18.
In a review of 193 patients with carcinoma of the tongue who underwent interstitial radiotherapy in our hospital from November 1978 to 1986, 5 year actuarial local control rate were 97%, 87%, 58% and 77% for T1, T2, T3 and T4 respectively. Mucosal ulcers with tissue defects and bone exposure of the mandible occurred in 5 years after the treatments, 6%, 22%, 44%, and 100% for T1, T2, T3 and T4, respectively. Therapeutic ratio was 1 in patients with T1 who underwent interstitial radiotherapy (70 Gy/7 days) alone while it was less than 1 in those with T2 or more. Therapeutic gain factor was less than 1 in patients with combined external radiotherapy.
在对1978年11月至1986年在我院接受间质放疗的193例舌癌患者进行的回顾中，T1、T2、T3和T4期患者的5年精算局部控制率分别为97%、87%、58%和77%。治疗后5年内，T1、T2、T3和T4期患者分别有6%、22%、44%和100%出现伴有组织缺损的黏膜溃疡和下颌骨骨质暴露。仅接受间质放疗（70 Gy/7天）的T1期患者的治疗比为1，而T2期及以上患者的治疗比小于1。接受外照射联合放疗的患者的治疗增益因子小于1。
