Hiratsuka J, Imajo Y, Nishishita S, Matsumiya A, Numaguchi K, Nagase N, Kurozumi A
Dept. of Radiation Oncology, Kawasaki Medical School.
Gan No Rinsho. 1987 Oct;33(13):1701-4.
The effectiveness of radiation therapy for metastatic bone tumor in 61 patients with 80 lesions has been evaluated. Relief from pain resulted in 87% all the treated lesions and this continued for more than two years in eight lesions of seven patients. There was no statistical difference in the pain relief achieved among the sites and the histologies of the primary tumors, and also no difference was noted as to the treated regions. Pain relief from the lesions of a squamous cell carcinoma tended to begin with smaller doses when compared with that of an adenocarcinoma. Our results suggest that radiation therapy in general appears to be an effective technique in achieving long term control of pain, but for some patients those with a generalized metastases or an uncontrolled primary tumor, for example, this tedious treatment has limited value and so should be withheld.
对61例患者共80处转移性骨肿瘤病灶的放射治疗效果进行了评估。87%的治疗病灶疼痛得到缓解，7例患者的8处病灶疼痛缓解持续超过两年。原发肿瘤的部位和组织学类型在疼痛缓解方面无统计学差异，治疗区域之间也无差异。与腺癌相比，鳞状细胞癌病灶的疼痛缓解往往从小剂量开始。我们的结果表明，总体而言，放射治疗似乎是实现疼痛长期控制的有效技术，但对于一些患者，例如那些有广泛转移或原发肿瘤未得到控制的患者，这种繁琐的治疗价值有限，因此应避免使用。
