骨转移瘤的放射治疗——特别提及缓解疼痛的效果

[Radiotherapy in bone metastases--with special reference to its effect on relieving pain].

作者信息

Murai N, Koga K, Nagamachi S, Nishikawa K, Matsuki K, Kusumoto S, Watanabe K

机构信息

Dept. of Radiology, Miyazaki Medical College.

出版信息

Gan No Rinsho. 1989 Sep;35(10):1149-52.

PMID:2550686

Abstract

Between December 1986 and January 1978, 68 patients with bone metastases were analyzed to evaluate the effect of radiation for the relief of pain. The 68 patients, who had a total of 97 lesions, complained of pain caused by their bone metastasis. The good, fair, and poor responses were found to be 18%, 60%, and 22%, respectively. With reference to the primary neoplasms, the effective response rate was 73% in lung cancer, 100% in breast cancer, 75% in gastric cancer, 100% in hepatic cancer, 100% in bladder cancer, 25% in epipharyngeal cancer, and 70% in the other neoplasms. Depending on the cell types of the lung cancer, the effective response rate was 80% for small cell carcinomas, 72% for adenocarcinomas and 40% for squamous cell carcinomas. Our results suggest that radiotherapy for bone metastases is to be recommended, since the effective response rate was 78% for the relief of pain.

摘要

在1986年12月至1978年1月期间，对68例骨转移患者进行了分析，以评估放疗缓解疼痛的效果。这68例患者共有97处病灶，均因骨转移而疼痛。结果发现，良好、一般和差的缓解率分别为18%、60%和22%。就原发肿瘤而言，肺癌的有效缓解率为73%，乳腺癌为100%，胃癌为75%，肝癌为100%，膀胱癌为100%，鼻咽癌为25%，其他肿瘤为70%。根据肺癌的细胞类型，小细胞癌的有效缓解率为80%，腺癌为72%，鳞状细胞癌为40%。我们的结果表明，骨转移放疗值得推荐，因为缓解疼痛的有效缓解率为78%。