Murai N, Koga K, Nagamachi S, Nishikawa K, Matsuki K, Kusumoto S, Watanabe K
Dept. of Radiology, Miyazaki Medical College.
Gan No Rinsho. 1989 Sep;35(10):1149-52.
Between December 1986 and January 1978, 68 patients with bone metastases were analyzed to evaluate the effect of radiation for the relief of pain. The 68 patients, who had a total of 97 lesions, complained of pain caused by their bone metastasis. The good, fair, and poor responses were found to be 18%, 60%, and 22%, respectively. With reference to the primary neoplasms, the effective response rate was 73% in lung cancer, 100% in breast cancer, 75% in gastric cancer, 100% in hepatic cancer, 100% in bladder cancer, 25% in epipharyngeal cancer, and 70% in the other neoplasms. Depending on the cell types of the lung cancer, the effective response rate was 80% for small cell carcinomas, 72% for adenocarcinomas and 40% for squamous cell carcinomas. Our results suggest that radiotherapy for bone metastases is to be recommended, since the effective response rate was 78% for the relief of pain.
在1986年12月至1978年1月期间，对68例骨转移患者进行了分析，以评估放疗缓解疼痛的效果。这68例患者共有97处病灶，均因骨转移而疼痛。结果发现，良好、一般和差的缓解率分别为18%、60%和22%。就原发肿瘤而言，肺癌的有效缓解率为73%，乳腺癌为100%，胃癌为75%，肝癌为100%，膀胱癌为100%，鼻咽癌为25%，其他肿瘤为70%。根据肺癌的细胞类型，小细胞癌的有效缓解率为80%，腺癌为72%，鳞状细胞癌为40%。我们的结果表明，骨转移放疗值得推荐，因为缓解疼痛的有效缓解率为78%。
