Fong Si-Lei, Dy Closas Alfand Marl F, Lim Thien Thien, Lean Phooi Leng, Loh Ee Chin, Lim Shen-Yang, Tan Ai Huey
Division of Neurology, Department of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Island Hospital, Penang, Malaysia.
Parkinsonism Relat Disord. 2023 Apr;109:105332. doi: 10.1016/j.parkreldis.2023.105332. Epub 2023 Mar 2.
The diagnostic approach to sleep-related movements disorders is seldom discussed. We report a case of fatal familial insomnia who initially presented with persistent limb movements in sleep, which later progressed to a state of agrypnia excitata. Here, the evaluation of abnormal movements in sleep is discussed using a step-by-step diagnostic approach. Although no cure is available for fatal familial insomnia, prompt recognition of this condition is important to facilitate proper management, including the involvement of interdisciplinary neuropalliative care.
睡眠相关运动障碍的诊断方法很少被讨论。我们报告一例致命性家族性失眠症患者，该患者最初表现为睡眠中持续的肢体运动，随后进展为激越性失眠状态。在此，我们使用逐步诊断方法讨论睡眠中异常运动的评估。尽管致命性家族性失眠症无法治愈，但及时识别这种疾病对于促进适当的管理很重要，包括跨学科神经姑息治疗的参与。
