Universidade Federal do Paraná, Hospital de Clínicas, Divisão de Neurologia, Curitiba PR, Brasil.
Arq Neuropsiquiatr. 2023 Feb;81(2):107-111. doi: 10.1055/s-0042-1758397. Epub 2023 Mar 22.
Stroke is one of the major causes of disability and mortality worldwide. Up to 30% of individuals who experience stroke die within 30 days, and more than 50% of those who survive will have some degree of disability. There are some predetermining factors based on admission data that could be used to objectively assess the odds of poor outcomes, including the Ischemic Stroke Predictive Risk Score (IScore).
To analyze and validate the IScore in patients undergoing intravenous thrombolysis for stroke and compare the results of this predictor with actual death and disability outcomes.
In a retrospective study, data were collected from a database housed at the Stroke Unit of the Teaching Hospital of Universidade Federal do Paraná, Southern Brazil. The IScore was applied to admission data from 239 patients, and the results were compared with actual outcomes (death and disability) within 30 days and 1 year after the stroke event. Data analysis was performed using an analysis of the receiver operating characteristic (ROC) curve to determine the sensitivity and specificity of the IScore in the study population.
The IScore demonstrated moderate sensitivity and high specificity in patients with stroke who underwent thrombolysis when evaluated after 30 days and 1 year of the event.
The IScore can be applied to in stroke patients undergoing thrombolysis; therefore, it may be used as an objective prognostic tool to guide clinical decision-making. Understanding the prognosis of patients in the acute phase can assist clinicians in making the best therapeutic decisions and enable better end-of-life care.
中风是全球范围内导致残疾和死亡的主要原因之一。多达 30%的中风患者在 30 天内死亡，超过 50%的幸存者将有一定程度的残疾。根据入院数据有一些预测因素，可以客观地评估不良预后的可能性，包括缺血性中风预测风险评分（IScore）。
分析和验证接受静脉溶栓治疗的中风患者的 IScore，并将该预测因子的结果与实际死亡和残疾结果进行比较。
在一项回顾性研究中，从巴西南部联邦大学教学医院中风科的数据库中收集数据。将 IScore 应用于 239 名患者的入院数据，并将结果与中风事件后 30 天和 1 年内的实际结局（死亡和残疾）进行比较。使用接收器操作特性（ROC）曲线分析对数据进行分析，以确定 IScore 在研究人群中的敏感性和特异性。
IScore 在接受溶栓治疗的中风患者中，在事件发生后 30 天和 1 年评估时，具有中度敏感性和高特异性。
IScore 可应用于接受溶栓治疗的中风患者；因此，它可以作为一种客观的预后工具，指导临床决策。了解急性期患者的预后情况可以帮助临床医生做出最佳治疗决策，并为临终关怀提供更好的支持。
