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血管质量倡议评估对血管外科学会临床实践指南中关于颅外脑血管病管理的依从情况。

Vascular Quality Initiative assessment of compliance with Society for Vascular Surgery clinical practice guidelines on the management of extracranial cerebrovascular disease.

机构信息

Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

Department of Surgery, West Virginia University-Charleston Division, Charleston, WV.

出版信息

J Vasc Surg. 2023 Jul;78(1):111-121.e2. doi: 10.1016/j.jvs.2023.03.026. Epub 2023 Mar 21.

Abstract

OBJECTIVES

Compliance with Society for Vascular Surgery (SVS) clinical practice guidelines (CPGs) is associated with improved outcomes for the treatment of abdominal aortic aneurysm, but this has not been assessed for carotid artery disease. The Vascular Quality Initiative (VQI) registry was used to examine compliance with the SVS CPGs for the management of extracranial cerebrovascular disease and its impact on outcomes.

METHODS

The 2021 SVS extracranial cerebrovascular disease CPGs were reviewed for evaluation by VQI data. Compliance rates by the center and provider were calculated, and the impact of compliance on outcomes was assessed using logistic regression with inverse probability-weighted risk adjustment for each CPG recommendation, allowing for clustering by the center. Our primary outcome was a composite end point of in-hospital stroke/death. As a secondary analysis, compliance with the 2021 SVS carotid implementation document recommendations and associated outcomes were also assessed.

RESULTS

Of the 11 carotid CPG recommendations, 4 (36%) could be evaluated using VQI registry data. Median center-specific CPG compliance ranged from 38% to 95%, and median provider-specific compliance ranged from 36% to 100%. After adjustment, compliance with 2 of the recommendations was associated with lower rates of in-hospital stroke/death: first, the use of best medical therapy (antiplatelet and statin therapy) in low/standard surgical risk patients undergoing carotid endarterectomy for >70% asymptomatic stenosis (event rate in compliant vs noncompliant cases 0.59% vs 1.3%; adjusted odds ratio: 0.44, 95% confidence interval: 0.29-0.66); and second, carotid endarterectomy over transfemoral carotid artery stenting in low/standard surgical risk patients with >50% symptomatic stenosis (1.9% vs 3.4%; adjusted odds ratio: 0.55, 95% confidence interval: 0.43-0.71). Of the 132 implementation document recommendations, only 10 (7.6%) could be assessed using VQI data, with median center- and provider-specific compliance rates ranging from 67% to 100%. The impact of compliance on outcomes could only be assessed for 6 (4.5%) of these recommendations, and compliance with all 6 recommendations was associated with lower stroke/death.

CONCLUSIONS

Few SVS recommendations could be assessed in the VQI because of incongruity between the recommendations and the VQI data variables collected. Although guideline compliance was extremely variable among VQI centers and providers, compliance with most of these recommendations was associated with improved outcomes after carotid revascularization. This finding confirms the value of guideline compliance, which should be encouraged for centers and providers. Optimization of VQI data to promote evaluation of guideline compliance and distribution of these findings to VQI centers and providers will help facilitate quality improvement efforts in the care of vascular patients.

摘要

目的

遵守血管外科学会(SVS)临床实践指南(CPG)与改善腹主动脉瘤治疗的结果相关,但尚未对颈动脉疾病进行评估。血管质量倡议(VQI)登记处用于检查遵守 SVS 关于治疗颅外脑血管疾病的 CPG 及其对结果的影响。

方法

审查 2021 年 SVS 颅外脑血管疾病 CPG 以进行 VQI 数据评估。计算中心和提供者的依从率,并使用逻辑回归评估每个 CPG 推荐的依从性对结果的影响,对每个 CPG 推荐进行反向概率加权风险调整,并按中心进行聚类。我们的主要结局是医院内卒中/死亡的复合终点。作为次要分析,还评估了遵守 2021 年 SVS 颈动脉实施文件建议及其相关结果。

结果

在 11 项颈动脉 CPG 建议中,有 4 项(36%)可以使用 VQI 登记处的数据进行评估。中位数中心特异性 CPG 依从率范围为 38%至 95%,中位数提供者特异性依从率范围为 36%至 100%。调整后,遵守 2 项建议与医院内卒中/死亡的发生率较低相关:第一,在接受颈动脉内膜切除术治疗无症状狭窄>70%的低/标准手术风险患者中使用最佳药物治疗(抗血小板和他汀类药物治疗)(符合条件的病例中事件发生率为 0.59%,不符合条件的病例中事件发生率为 1.3%;调整后的优势比:0.44,95%置信区间:0.29-0.66);其次,在低/标准手术风险患者中,对于有>50%症状性狭窄的患者,颈动脉内膜切除术优于经股颈动脉支架置入术(符合条件的病例中事件发生率为 1.9%,不符合条件的病例中事件发生率为 3.4%;调整后的优势比:0.55,95%置信区间:0.43-0.71)。在 132 项实施文件建议中,只有 10 项(7.6%)可以使用 VQI 数据进行评估,中心和提供者特异性依从率中位数范围为 67%至 100%。仅能评估其中 6 项(4.5%)建议对结果的影响,遵守所有 6 项建议均与卒中/死亡降低相关。

结论

由于建议与 VQI 收集的数据变量之间存在不一致,因此在 VQI 中只能评估少数 SVS 建议。尽管 VQI 中心和提供者之间的指南依从性差异很大,但这些建议的大部分遵守都与颈动脉血运重建后的结果改善相关。这一发现证实了指南依从性的价值,应该鼓励中心和提供者遵守。优化 VQI 数据以促进对指南依从性的评估,并将这些发现分发给 VQI 中心和提供者,将有助于促进血管患者护理质量改进工作。

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