Oedema: a rare complication of plasma donation in an adolescent female.

Plasma donation has been widely used to recover medically vital components, such as immunoglobulins and clotting factors. Although generally well tolerated, there have been reports in the medical literature of reactions following blood and plasma donation. We present the first case, to our knowledge, of lower extremity oedema as the only complication noted following plasma donation in an adolescent female without underlying risk factors. Laboratory evaluation was unremarkable with the exception of decreased total serum protein. Symptoms resolved with conservative management and avoidance of plasma donation. Our case highlights the importance of screening for all sources of income in adolescents to assess for health disparities, evaluate risk factors and provide appropriate guidance.