U.O. Immunoematologia e Trasfusione Sangue, Ospedale Misericordia e Dolce, Azienda USL4, Prato, Italy.
Blood Transfus. 2007 Jul;5(3):143-52. doi: 10.2450/2007.0005-07.
Voluntary donors normally tolerate blood donation very well, but, occasionally, adverse reactions of variable severity may occur during or at the end of the collection. Aim of this study was to estimate and possibly avoid the cause of unwanted reactions.
The study was conducted over a period of 6 months, from 24(th) October, 2005 to 24(th) April 2006. The donor population analysed consisted of 4,906 donors (3,716 male and 1,190 female). In total, 3,983 (81%) voluntaries have donated whole blood, 851 (17%) plasma from apheresis, 64 (1.3%) experienced multicomponent donation, and 8 (0.1%) were donors of plasma-platelet apheresis.
Only 63 donors (1.2% of all the volunteers) suffered some kind of adverse reaction: 59 (1.08% of the subjects) had mild reactions (agitation, sweating, pallor, cold feeling, sense of weakness, nausea), and only 4 (3 males and 1 female, 0.2%) had more severe disorders, including vomiting, loss of consciousness, and convulsive syncope.
Although the number of donors who developed disturbances during or at the end of blood donations was very low, it is nevertheless desirable to reduce risks to a minimum. A set of advices is provided for preventing problems.
自愿献血者通常能很好地耐受献血，但偶尔在采血过程中或结束时会出现不同严重程度的不良反应。本研究旨在评估并尽可能避免这些不良反应的发生原因。
该研究在 2005 年 10 月 24 日至 2006 年 4 月 24 日期间进行了 6 个月，分析的献血人群包括 4906 名献血者（3716 名男性和 1190 名女性）。共有 3983 名（81%）志愿者捐献了全血，851 名（17%）来自单采血浆，64 名（1.3%）接受了多成分捐献，8 名（0.1%）为血小板单采血浆捐献者。
仅有 63 名献血者（占所有志愿者的 1.2%）出现了某种不良反应：59 名（占献血者的 1.08%）为轻度反应（躁动、出汗、苍白、发冷感、虚弱感、恶心），仅 4 名（3 名男性和 1 名女性，0.2%）出现更严重的紊乱，包括呕吐、失去意识和惊厥性晕厥。
尽管在采血过程中或结束时出现紊乱的献血者人数非常低，但仍希望将风险降至最低。为预防问题，提供了一套建议。
