骨质疏松症：老龄化人口的病因、机制和管理方法综述。

Osteoporosis: Review of Etiology, Mechanisms, and Approach to Management in the Aging Population.

机构信息

Rush University Medical Center, 1611 West Harrison Suite 510, Chicago, IL 60612, USA.

University of California at Davis School of Medicine.

出版信息

Endocrinol Metab Clin North Am. 2023 Jun;52(2):259-275. doi: 10.1016/j.ecl.2022.10.009. Epub 2023 Feb 19.

DOI:10.1016/j.ecl.2022.10.009

PMID:36948779

Abstract

Osteoporosis is the most common metabolic bone disease. With special respect to the aging population, it is very common, not only due to changes in lifestyle and diet but as a result of the aging process there is low-grade inflammation and immune system activation that directly affects bone strength and quality. This article provides a review of the incidence, etiology, and approach to screening and management of osteoporosis in the aging population. A thorough screening of lifestyle, environmental, and clinical conditions will be reviewed which identifies appropriate candidates for screening and treatment.

摘要

骨质疏松症是最常见的代谢性骨病。随着人口老龄化，骨质疏松症非常普遍，不仅由于生活方式和饮食的改变，而且由于衰老过程中存在低度炎症和免疫系统激活，直接影响骨强度和质量。本文综述了老龄化人口中骨质疏松症的发病率、病因以及筛查和管理方法。将彻底筛查生活方式、环境和临床状况，以确定适合进行筛查和治疗的合适人选。