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28 岁孕妇发生严重巨细胞病毒肺炎及由此导致的急性呼吸窘迫综合征:病例报告。

Severe CMV pneumonitis and the resulting ARDS in a 28-year-old pregnant woman: a case report.

机构信息

Department of Obstetrics and Gynecology, Patra University School of Medicine, 26504, Patra, Greece.

出版信息

BMC Infect Dis. 2023 Mar 22;23(1):176. doi: 10.1186/s12879-023-08091-5.

Abstract

BACKGROUND

Cytomegalovirus (CMV) is a common virus. In pregnant women, CMV infection is usually mildly symptomatic or asymptomatic but can lead to fetal infection. Here we present a rare case of severe CMV pneumonitis and acute respiratory distress syndrome in a healthy immunocompetent pregnant woman.

CASE PRESENTATION

A previous healthy 28-year-old woman with spontaneous conception, was admitted to the General University Hospital of Patras at 29 weeks of gestation with a day history of fever, fatigue, pharyngitis, and cough. She was diagnosed with acute CMV infection and CMV pneumonitis. During her hospitalization she developed acute distress syndrome (ARDS). The patient was intubated and underwent emergency caesarean delivery. She was admitted to the intensive care unit and received intravenous ganciclovir. She was discharged at 20th day postpartum in a good clinical condition.

CONCLUSIONS

This case highlights the infrequent yet potential complexity of CMV infection in immunocompetent patients and in pregnancy.

摘要

背景

巨细胞病毒(CMV)是一种常见的病毒。在孕妇中,CMV 感染通常症状轻微或无症状,但可导致胎儿感染。这里我们报告一例健康免疫能力健全的孕妇罕见的严重 CMV 肺炎和急性呼吸窘迫综合征病例。

病例介绍

一位既往健康的 28 岁女性,自发性受孕,于妊娠 29 周时因发热、乏力、咽炎和咳嗽 1 天而入住帕特拉大学总医院。她被诊断为急性 CMV 感染和 CMV 肺炎。住院期间,她发生急性呼吸窘迫综合征(ARDS)。患者行气管插管并接受紧急剖宫产。她被收入重症监护病房,并接受更昔洛韦静脉滴注。患者在产后第 20 天出院,临床状况良好。

结论

本病例强调了免疫能力健全的患者和妊娠期间 CMV 感染的罕见但潜在的复杂性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cfe/10035251/d44e82668030/12879_2023_8091_Fig1_HTML.jpg

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