Ullah Faizan, Naeem Awais, Bakhtiar Nighat, Shakeel Osama, Khattak Shahid, Syed Aamir Ali
Dr. Faizan Ullah, Fellow Surgical Oncology, Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&RC), Lahore, Pakistan.
Dr. Awais Naeem, Fellow Surgical Oncology, Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&RC), Lahore, Pakistan.
Pak J Med Sci. 2023 Mar-Apr;39(2):371-376. doi: 10.12669/pjms.39.2.6613.
The objective of the study was to review the experience of dealing oncological emergency esophagectomies at a dedicated Cancer hospital.
We performed a retrospective review of data of eleven esophagectomies at the Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore (SKMCH&RC) Pakistan, from 1 January, 2009 to 30 June, 2019. Out of 590 oncological esophagectomies, eleven patients had emergency resection. We collected the data of demographics, primary disease, comorbidities, location of tumor and perforation, cause of perforations, radiological and endoscopic findings, clinical findings and follow-up visits after discharge. Data was analyzed by SPSS version 21 for windows.
All 11 patients out of five hunded ninety had esophageal cancer. At the time of initial staging, eight (72%) had locally advanced stage (stage III and IV). Open transhiatal approach was used in six (55%) patients, and the rest had three stage esophagectomies. Primary reconstructions with gastric conduit were performed in all, except in two (18%) patients, Respiratory complications were the most common of the encountered complications, seven (63%) of the patients had palliative resection. Ninety day mortality was observed in 3(27.3%) patients. On long term follow up, six patients had recurrence, with median Disease-Free Survival (DFS) 5.88 months and Median Overall Survival (OS) was 6.37 months. Out of 11, only three patients are alive without disease, while one patient is lost during follow-up.
Emergency esophagectomy is a lifesaving procedure; there should be multidisciplinary team approach towards the management. Early diagnosis and management is of paramount importance.
本研究的目的是回顾一家专业癌症医院处理肿瘤急症食管切除术的经验。
我们对巴基斯坦拉合尔绍卡特·汗姆纪念癌症医院及研究中心(SKMCH&RC)外科肿瘤学部门2009年1月1日至2019年6月30日期间的11例食管切除术数据进行了回顾性分析。在590例肿瘤性食管切除术中,11例患者接受了急诊切除。我们收集了人口统计学、原发性疾病、合并症、肿瘤及穿孔位置、穿孔原因、放射学和内镜检查结果、临床检查结果以及出院后随访的数据。数据采用适用于Windows的SPSS 21版进行分析。
590例患者中有11例患有食管癌。在初始分期时,8例(72%)为局部晚期(III期和IV期)。6例(55%)患者采用了开放经裂孔入路,其余患者接受了三阶段食管切除术。除2例(18%)患者外,所有患者均采用胃管道进行一期重建。呼吸并发症是最常见的并发症,7例(63%)患者接受了姑息性切除。3例(27.3%)患者观察到90天死亡率。长期随访中,6例患者复发,无病生存期(DFS)中位数为5.88个月;总生存期(OS)中位数为6.37个月。11例患者中,只有3例无病存活,1例在随访期间失访。
急诊食管切除术是一种挽救生命的手术;管理上应采用多学科团队方法。早期诊断和管理至关重要。