Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan.
Department of Psychiatry, Tokyo Women's Medical University, Tokyo, Japan.
Ann Clin Transl Neurol. 2023 May;10(5):832-835. doi: 10.1002/acn3.51764. Epub 2023 Mar 23.
A 30-year-old woman with tardive dystonia in the cervical region from long-term antipsychotic meds was treated with radiofrequency ablation of the right pallidothalamic tract in the fields of Forel. The patient showed improvement in both cervical dystonia and obsessive-compulsive disorder after the procedure, with 77.4% improvement in cervical dystonia and 86.7% improvement in obsessive-compulsive disorder. Although the treatment site in this case was intended to treat cervical dystonia, the lesion was located in the optimal stimulation network for both obsessive-compulsive disorder and cervical dystonia, suggesting that neuromodulation of this region could potentially treat both simultaneously.
一位 30 岁的女性因长期使用抗精神病药物而出现颈部迟发性运动障碍，接受了 Forel 区右侧苍白球丘脑束的射频消融术治疗。术后，患者的颈部肌张力障碍和强迫症均有改善，颈部肌张力障碍改善 77.4%，强迫症改善 86.7%。虽然本例的治疗靶点是治疗颈部肌张力障碍，但病变位于强迫症和颈部肌张力障碍的最佳刺激网络中，这表明该区域的神经调节可能有潜力同时治疗这两种疾病。
