多西环素接触后预防可能导致淋病奈瑟菌对其他类别的抗菌药物产生交叉耐药性：一项计算机模拟分析。
Doxycycline Postexposure Prophylaxis Could Induce Cross-Resistance to Other Classes of Antimicrobials in Neisseria gonorrhoeae : An In Silico Analysis.
机构信息
From the STI Unit, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
出版信息
Sex Transm Dis. 2023 Aug 1;50(8):490-493. doi: 10.1097/OLQ.0000000000001810. Epub 2023 Mar 23.
PMID:36952471
Abstract
We found that tetracycline resistance-associated mutations and genes in Neisseria gonorrhoeae are linked to mutations causing resistance to other antimicrobials. Therefore, the use of doxycycline postexposure prophylaxis may select for resistance to other antimicrobials.
摘要
我们发现淋病奈瑟菌中与四环素耐药相关的突变和基因与导致其他抗菌药物耐药的突变有关。因此，使用多西环素暴露后预防可能会选择对其他抗菌药物的耐药性。
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