肯尼亚高水平耐四环素淋病奈瑟菌流行：对全球推广多西环素暴露后预防以预防性传播感染的影响。
Predominance of High-Level Tetracycline-Resistant Neisseria gonorrhoeae in Kenya: Implications for Global Implementation of Doxycycline Postexposure Prophylaxis for Prevention of Sexually Transmitted Infections.
机构信息
Epidemiology.
From the Departments of Global Health.
出版信息
Sex Transm Dis. 2023 May 1;50(5):317-319. doi: 10.1097/OLQ.0000000000001769. Epub 2023 Jan 13.
Abstract
Using archived Neisseria gonorrhoeae samples from 2008 to 2012, the prevalence of tet (M) genemediating high-level tetracycline resistance in N. gonorrhoeae was 96% among 50 Kenyan women. Determining the local and national prevalence of gonococcal tetracycline resistance and surveillance of gonococcal antimicrobial resistance can inform the implementation of doxycycline postexposure prophylaxis for STI prevention.
摘要
利用 2008 年至 2012 年保存的淋病奈瑟菌样本，在 50 名肯尼亚女性中，高水平四环素耐药性的 tet (M) 基因介导的淋病奈瑟菌的流行率为 96%。确定淋病奈瑟菌对四环素的局部和全国耐药率以及淋病奈瑟菌对抗微生物药物耐药性的监测，可以为实施针对性传播感染的多西环素接触后预防提供信息。
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