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出生体重和胎龄对新生儿重症监护病房出院后再入院的修饰作用。

Birth Weight and Gestational Age as Modifiers of Rehospitalization after Neonatal Intensive Care Unit Admission.

机构信息

Children's Hospital of Orange County, Orange, California.

School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.

出版信息

Am J Perinatol. 2024 May;41(S 01):e1668-e1674. doi: 10.1055/a-2061-0059. Epub 2023 Mar 23.

DOI:10.1055/a-2061-0059
PMID:36958343
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11136569/
Abstract

OBJECTIVE

This study aimed to assess interaction effects between gestational age and birth weight on 30-day unplanned hospital readmission following discharge from the neonatal intensive care unit (NICU).

STUDY DESIGN

This is a retrospective study that uses the study site's Children's Hospitals Neonatal Database and electronic health records. Population included patients discharged from a NICU between January 2017 and March 2020. Variables encompassing demographics, gestational age, birth weight, medications, maternal data, and surgical procedures were controlled for. A statistical interaction between gestational age and birth weight was tested for statistical significance.

RESULTS

A total of 2,307 neonates were included, with 7.2% readmitted within 30 days of discharge. Statistical interaction between birth weight and gestational age was statistically significant, indicating that the odds of readmission among low birthweight premature patients increase with increasing gestational age, whereas decrease with increasing gestational age among their normal or high birth weight peers.

CONCLUSION

The effect of gestational age on odds of hospital readmission is dependent on birth weight.

KEY POINTS

· Population included patients discharged from a NICU between January 2017 and March 2020.. · A total of 2,307 neonates were included, with 7.2% readmitted within 30 days of discharge.. · The effect of gestational age on odds of hospital readmission is dependent on birth weight..

摘要

目的

本研究旨在评估新生儿重症监护病房（NICU）出院后 30 天内计划性住院再入院与胎龄和出生体重之间的交互作用。

研究设计

这是一项回顾性研究，使用了研究地点的儿童医院新生儿数据库和电子健康记录。纳入的患者为 2017 年 1 月至 2020 年 3 月期间从 NICU 出院的患者。控制了包括人口统计学、胎龄、出生体重、药物、产妇数据和手术程序在内的变量。测试了胎龄和出生体重之间的统计学交互作用是否具有统计学意义。

结果

共有 2307 名新生儿纳入研究，出院后 30 天内有 7.2%的新生儿再次入院。胎龄和出生体重之间的统计学交互作用具有统计学意义，表明低出生体重早产儿的再入院几率随着胎龄的增加而增加，而其正常或高出生体重的同龄人则随着胎龄的增加而减少。

结论

胎龄对住院再入院几率的影响取决于出生体重。

关键点

· 研究人群包括 2017 年 1 月至 2020 年 3 月期间从 NICU 出院的患者。· 共有 2307 名新生儿纳入研究，出院后 30 天内有 7.2%的新生儿再次入院。· 胎龄对住院再入院几率的影响取决于出生体重。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e902/11136569/262a835f1c65/10-1055-a-2061-0059-i22oct1644-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e902/11136569/262a835f1c65/10-1055-a-2061-0059-i22oct1644-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e902/11136569/262a835f1c65/10-1055-a-2061-0059-i22oct1644-1.jpg

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