Department of Chemistry, Malaviya National Institute of Technology Jaipur, Jaipur 302017, India.
Materials Research Centre, Malaviya National Institute of Technology Jaipur, Jaipur 302017, India.
Int J Biol Macromol. 2023 May 31;238:124145. doi: 10.1016/j.ijbiomac.2023.124145. Epub 2023 Mar 22.
Antibiotic resistance is increasing globally due to increased prescription and easy dispensing of antibiotic drugs universally. Hence, to mitigate this effect, efficient, biodegradable, and non-toxic adsorbents are required to be developed. Carrageenan (CG), a natural polymer, having multiple functional groups, provides a backbone for crosslinking with borax and incorporation of ZnO nanoparticles that formed borax-cross-linked κ-carrageenan (CG/Bx/ZnO) hydrogel which is used for efficient adsorption of norfloxacin from water. Surface morphology of as-synthesized hydrogel revealed the rough surface, which was determined by FESEM. Surface area of CG/Bx/ZnO hydrogel was found to be 22.90 m/g with 3.41 nm pore radius. Systematic batch adsorption studies revealed that 99.4 % removal efficiency could be achieved at a dosage level of 20 mg/L of norfloxacin with 10 mg of hydrogel at pH of 4 in 8 h at room temperature. Experimentally optimized key parameters affecting the overall efficiency of adsorption matched well with the results assessed from ANOVA using Box-Behnken composite design model. The adsorption process was well fitted with the pseudo-second-order model and Langmuir isotherm with 1282.05 mg/g adsorption capacity. Thermodynamic study results show that adsorption is spontaneous and endothermic. The CG/Bx/ZnO hydrogel demonstrated excellent repeatability with minimal loss in norfloxacin adsorption for seven cycles.
由于抗生素药物的处方和普遍使用增加，全球的抗生素耐药性正在增加。因此，需要开发高效、可生物降解和无毒的吸附剂来缓解这种影响。卡拉胶（CG）是一种具有多种官能团的天然聚合物，为与硼砂交联和掺入氧化锌纳米粒子提供了骨架，形成了硼砂交联κ-卡拉胶（CG/Bx/ZnO）水凝胶，用于从水中高效吸附诺氟沙星。合成水凝胶的表面形态显示出粗糙的表面，这是由 FESEM 确定的。CG/Bx/ZnO 水凝胶的表面积为 22.90 m/g，孔径为 3.41 nm。系统的批处理吸附研究表明，在 pH 为 4 的条件下，在室温下 8 小时内，以 20 mg/L 的诺氟沙星剂量和 10 mg 的水凝胶可以达到 99.4%的去除效率。实验优化的影响吸附整体效率的关键参数与使用 Box-Behnken 复合设计模型的方差分析评估的结果非常吻合。吸附过程很好地符合伪二阶模型和 Langmuir 等温线，吸附容量为 1282.05 mg/g。热力学研究结果表明，吸附是自发和吸热的。CG/Bx/ZnO 水凝胶在七个循环中表现出良好的可重复性，对诺氟沙星的吸附损失最小。
