Noma Tomoko, Kayo Godai, Kabayama Mai, Gondo Yasuyuki, Yasumoto Saori, Masui Yukie, Sugimoto Ken, Akasaka Hiroshi, Takami Yoichi, Takeya Yasushi, Yamamoto Koichi, Ikebe Kazunori, Arai Yasumichi, Ishizaki Tatsuro, Rakugi Hiromi, Kamide Kei
Department of Nutrition, College of Nutrition, Koshien University, Takarazuka, Japan.
Department of Health Sciences, Graduate School of Medicine, Osaka University, Osaka, Japan.
Geriatr Gerontol Int. 2023 May;23(5):334-340. doi: 10.1111/ggi.14571. Epub 2023 Mar 23.
The aging-related increase in the incidence of anemia potentially affects the mortality risk. Lower cognitive function is common among older adults, and anemia is one of the causes of cognitive decline. However, to the best of our knowledge, no study has investigated whether cognitive decline is a risk factor for anemia in older people. Therefore, in this study, we used a 3-year longitudinal evaluation to examine the association of cognitive function with anemia in community-dwelling older adults.
This longitudinal study enrolled participants without anemia (diagnosed based on the World Health Organization's criteria) at baseline. Cognitive function was assessed using the Japanese version of the Montreal Cognitive Assessment. Multiple logistic regression models were used to examine the association between cognitive function at baseline and the presence of anemia 3 years later.
Participants were in the 69-71 and 79-81 years age groups, and 974 older people (48.6% men) were enrolled, of whom 126 (12.9%) had anemia after 3 years. After adjusting, cognitive function at baseline was associated with anemia in women, but not in men.
Older Japanese women with lower cognitive function have an increased risk for anemia 3 years later. The adoption of a lifestyle that utilizes or improves cognitive function might be important to prevent anemia in older women. Geriatr Gerontol Int 2023; 23: 334-340.
与衰老相关的贫血发病率增加可能会影响死亡风险。认知功能下降在老年人中很常见，贫血是认知衰退的原因之一。然而，据我们所知，尚无研究调查认知衰退是否是老年人贫血的危险因素。因此，在本研究中，我们采用了为期3年的纵向评估，以研究社区居住的老年人认知功能与贫血之间的关联。
这项纵向研究纳入了基线时无贫血（根据世界卫生组织标准诊断）的参与者。使用蒙特利尔认知评估的日语版本评估认知功能。采用多元逻辑回归模型来研究基线时的认知功能与3年后贫血的存在之间的关联。
参与者年龄在69 - 71岁和79 - 81岁年龄组，共纳入974名老年人（48.6%为男性），其中126人（12.9%）在3年后出现贫血。调整后，基线时的认知功能与女性贫血有关，但与男性无关。
认知功能较低的日本老年女性在3年后患贫血的风险增加。采用利用或改善认知功能的生活方式可能对预防老年女性贫血很重要。《老年医学与老年病学国际杂志》2023年；23: 334 - 340。
