Tseitlina E A, Lanskaia I M, Marchenko A L, Rolikhin A E, Sevast'ianov V I
Med Tekh. 1987 Sep-Oct(5):39-43.
A quantitative criterion of the activation of the patient's complement during hemodialysis has been worked out on the basis of the proposed mathematical model. It has been shown that the activation of the complement system observed during hemodialysis and the negative clinical effects (leukopenia, hypoxia) accompanying it depend both on the membrane properties and the patient's individual response. A possibility has been revealed of using the above criterion for the individual choice of hemodialytic membranes in order to reduce the negative clinical effects connected with the activation of the complement system.
基于所提出的数学模型，已制定出一种用于评估血液透析过程中患者补体激活的定量标准。结果表明，血液透析过程中观察到的补体系统激活及其伴随的负面临床效应（白细胞减少、缺氧）既取决于膜的特性，也取决于患者的个体反应。已揭示出利用上述标准来个体化选择血液透析膜的可能性，以便减少与补体系统激活相关的负面临床效应。
