肠胶质细胞：基因组开放，处于准备状态，随时可以生成神经元。

Enteric glia: genomically open, poised, and ready to make neurons.

机构信息

Department of Pathology and Cell Biology, Columbia University Vagelos College of Physicians and Surgeons, 630 West 168th Street, New York, NY 10032, USA.

出版信息

Trends Cell Biol. 2023 Jun;33(6):446-448. doi: 10.1016/j.tcb.2023.03.005. Epub 2023 Mar 21.

DOI:10.1016/j.tcb.2023.03.005

PMID:36958997

Abstract

The heterogeneity and multiple functions of enteric glia have recently been recognized. Guyer et al. have now confirmed the neurogenetic potential of enteric glial cells and have also found that some have an open chromatin configuration, suggesting that some glial cells are poised and ready to differentiate into neurons.

摘要

近年来，人们已经认识到肠胶质细胞的异质性和多种功能。现在，盖耶等人已经证实了肠胶质细胞的神经发生潜能，并且还发现其中一些细胞具有开放的染色质构型，这表明一些胶质细胞已经准备好分化为神经元。