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肠神经系统中的神经元和神经胶质与上皮屏障功能

Neurons and Glia in the Enteric Nervous System and Epithelial Barrier Function.

机构信息

IRSD, Université de Toulouse, INSERM, INRA, ENVT, UPS, Toulouse , France.

Department of Physiology and Pharmacology, Faculty of Medicine, University of Calgary , Calgary, Alberta , Canada.

出版信息

Physiology (Bethesda). 2018 Jul 1;33(4):269-280. doi: 10.1152/physiol.00009.2018.

DOI:10.1152/physiol.00009.2018
PMID:29897300
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6088142/
Abstract

The intestinal epithelial barrier is the largest exchange surface between the body and the external environment. Its functions are regulated by luminal, and also internal, components including the enteric nervous system. This review summarizes current knowledge about the role of the digestive "neuronal-glial-epithelial unit" on epithelial barrier function.

摘要

肠道上皮屏障是机体与外界环境之间最大的交换表面。其功能受腔(内)和(内)部成分的调节,包括肠神经系统。本文综述了目前关于消化“神经元-胶质-上皮单元”在上皮屏障功能中的作用的知识。

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J Surg Res. 2017 Nov;219:214-221. doi: 10.1016/j.jss.2017.05.099. Epub 2017 Jun 30.
2
Neuroimmune interaction and the regulation of intestinal immune homeostasis.神经免疫相互作用与肠道免疫稳态的调节。
Am J Physiol Gastrointest Liver Physiol. 2018 Jan 1;314(1):G75-G80. doi: 10.1152/ajpgi.00425.2016. Epub 2017 Sep 14.
3
Enteric Glia Regulate Gastrointestinal Motility but Are Not Required for Maintenance of the Epithelium in Mice.肠神经胶质细胞调节胃肠蠕动,但对维持小鼠上皮细胞并非必需。
Gastroenterology. 2017 Oct;153(4):1068-1081.e7. doi: 10.1053/j.gastro.2017.07.002. Epub 2017 Jul 13.
4
The Enteric Network: Interactions between the Immune and Nervous Systems of the Gut.肠道网络:肠道免疫系统与神经系统之间的相互作用
Immunity. 2017 Jun 20;46(6):910-926. doi: 10.1016/j.immuni.2017.05.011.
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Lineage-dependent spatial and functional organization of the mammalian enteric nervous system.哺乳动物肠神经系统的谱系依赖性空间和功能组织。
Science. 2017 May 19;356(6339):722-726. doi: 10.1126/science.aam7511.
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Front Cell Neurosci. 2017 Apr 25;11:118. doi: 10.3389/fncel.2017.00118. eCollection 2017.
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