Thebridge Linda, Fisher Charles, Puttaswamy Vikram, Pollock Carol, Clarke Jillian
University of Sydney, Camperdown, Australia; Department of Vascular Surgery, Royal North Shore Hospital, St Leonards, Australia.
University of Sydney, Camperdown, Australia; Department of Vascular Surgery, Royal North Shore Hospital, St Leonards, Australia.
Transplant Proc. 2023 Apr;55(3):569-575. doi: 10.1016/j.transproceed.2023.02.055. Epub 2023 Mar 21.
While intra-operative duplex ultrasound scanning can be readily performed in renal transplantation, the value of this intervention in routine practice is not established.
Three hundred thirty-one consecutive single renal transplants in adult recipients underwent intraoperative scanning at implantation. Early graft losses were compared with those recorded in the ANZDATA Registry.
Nine overt vascular abnormalities were corrected prior to scanning. Four further suspected venous outflow restrictions were confirmed by ultrasound and revised. Another 11 major vascular revisions were performed following intraoperative ultrasound consisting of 7 otherwise unsuspected inflow abnormalities, all corrected, and 4 anastomoses redone to reposition the graft. Thirty-two (9.7%) grafts were repositioned under ultrasound guidance to improve cortical perfusion but without vascular revision. One graft with hyperacute rejection was explanted 4 days postimplantation and one graft with primary nonfunction remained well perfused. Two patients died within 90 days, both with functioning grafts. Twenty-three grafts were re-explored within 7 days, including 9 solely for graft hypoperfusion. There were no postoperative arterial thromboses and, at re-exploration, no arterial anastomoses required revision. There were no postoperative venous thromboses, although one venous anastomosis was revised. No grafts were lost within 90 days for surgical or technical reasons compared with 76 (1.0%) of 7603 contemporaneous grafts in the ANZDATA Registry (P = .077 Fisher's exact test, P = .069 χ test).
The routine use of intraoperative ultrasound appears to be of benefit by identifying otherwise unrecognized vascular abnormalities, leading to a reduction in early graft losses because of surgical factors.
虽然术中双功超声扫描在肾移植中易于实施,但该干预措施在常规实践中的价值尚未确立。
331例成年受者接受的连续单肾移植在植入时进行了术中扫描。将早期移植肾丢失情况与澳大利亚和新西兰透析与移植登记处(ANZDATA Registry)记录的情况进行比较。
9例明显的血管异常在扫描前得到纠正。另外4例怀疑的静脉流出道受限经超声证实并进行了修正。术中超声检查后又进行了11次主要血管修正,包括7例原本未被怀疑的流入道异常,均得到纠正,以及4例重新进行吻合以重新放置移植肾。32例(9.7%)移植肾在超声引导下重新定位以改善皮质灌注,但未进行血管修正。1例发生超急性排斥反应的移植肾在植入后4天被切除,1例原发性无功能的移植肾仍灌注良好。2例患者在90天内死亡,二者的移植肾均功能良好。23例移植肾在7天内再次探查,其中9例仅因移植肾灌注不足。术后无动脉血栓形成,再次探查时无需修正动脉吻合口。术后无静脉血栓形成,尽管有1例静脉吻合口进行了修正。与澳大利亚和新西兰透析与移植登记处7603例同期移植肾中的76例(1.0%)相比,90天内无移植肾因手术或技术原因丢失(Fisher精确检验P = 0.077,χ检验P = 0.069)。
术中超声的常规使用似乎有益,可识别出原本未被发现的血管异常,从而减少因手术因素导致的早期移植肾丢失。