Singh Sucheta, Tehlan Sumit, Kumar Verma Prabhakar
Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, 124001, India.
ICMR-Vector Control Research Centre, Puducherry, 605006, India.
Mini Rev Med Chem. 2023;23(22):2142-2165. doi: 10.2174/1389557523666230320164203.
Heterocyclic compounds have diverse structure, which makes them broad and economical therapeutic agents. Pyrazole is a five-membered aromatic ring that contains two nitrogen atom and is responsible for the diverse functions of heterocyclic compounds. This implies the need of reviewing the work that already has been done on the potential of pyrazole scaffolds in the field of medicinal chemistry for the synthesis of new compounds with more effective antimicrobial, antioxidant, anticancer, anti-tuberculosis, and anti-inflammatory activities.
杂环化合物具有多样的结构，这使其成为广泛且经济的治疗剂。吡唑是一个含有两个氮原子的五元芳香环，它赋予了杂环化合物多样的功能。这意味着有必要回顾一下在药物化学领域中已经开展的关于吡唑骨架在合成具有更有效抗菌、抗氧化、抗癌、抗结核和抗炎活性的新化合物方面潜力的研究工作。
