BSN, Imam Khomeini Teaching Hospital, Wound Manager, Urmia, IR, Iran.
Department of Medical Education, School of Medicine, Urmia University of Medical Sciences, Urmia, IR, Iran.
Childs Nerv Syst. 2023 Jul;39(7):1969-1976. doi: 10.1007/s00381-023-05929-w. Epub 2023 Mar 24.
Surgical site infection (SSI) prolongs the treatment period, delays wound healing, increases antibiotic consumption, and leads to patient death in complicated cases. This case was a 10-day female infant born at 37-week- and 6-day of gestational age with a birth weight of 3700 g and Apgar 5/8 by emergency cesarean section due to spina bifida cystica with myelomeningocele (MMC). She was admitted to the neonatal intensive care unit (NICU) because of respiratory distress and hypotonic lower extremities on June 2, 2022. A cardiovascular and neurosurgery consult was okay for reconstructive surgery, and she had MMC repair surgery by a plastic surgeon on June 5, 2022. The surgical site was infected, and SSI had no improvement, despite regularly receiving wet and Vaseline gauze dressing and intravenous antibiotic therapy. We started the treatment using Medihoney™, honey antibacterial wound dressing, on SSI once a day for 2 weeks, then once every other day for the next 6 weeks. Her SSI was cured entirely after 2 months, and she was discharged from our wound treatment team in satisfactory general condition. Clinicians and wound care management teams could use honey antibacterial wound gel to treat SSI, particularly in newborns with weakened immune systems after spinal birth defects repair.
手术部位感染(SSI)会延长治疗期、延迟伤口愈合、增加抗生素的使用,并在复杂情况下导致患者死亡。本病例为 1 名 10 天女婴,孕 37 周+6 天因囊性脊柱裂伴脊髓脊膜膨出行急诊剖宫产,出生体重 3700g,Apgar 评分 5/8。因呼吸窘迫和下肢无力于 2022 年 6 月 2 日入住新生儿重症监护病房(NICU)。心血管和神经外科会诊认为可以进行重建手术,6 月 5 日由整形外科医生行脊髓脊膜膨出修补术。手术部位感染,尽管定期接受湿性凡士林纱布换药和静脉抗生素治疗,SSI 仍无改善。我们开始使用 Medihoney™,一种具有抗菌作用的蜂蜜创面敷料,每天治疗 SSI 一次,持续 2 周,然后每隔一天治疗一次,持续 6 周。2 个月后,她的 SSI 完全治愈,一般状况良好出院。临床医生和伤口护理管理团队可以使用具有抗菌作用的蜂蜜创面凝胶治疗 SSI,特别是在脊柱出生缺陷修复后免疫系统较弱的新生儿中。