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ABO 血型不合新生儿直接抗球蛋白试验阴性时的光疗比例。

Rates of phototherapy among ABO-incompatible newborns with a negative direct antiglobulin test.

机构信息

Department of Medicine, Boston Children's Hospital, Boston, MA, USA.

Department of Pediatrics, Boston Medical Center, Boston, MA, USA.

出版信息

J Perinatol. 2023 Nov;43(11):1357-1362. doi: 10.1038/s41372-023-01650-3. Epub 2023 Mar 23.

DOI:10.1038/s41372-023-01650-3
PMID:36959468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10034253/
Abstract

OBJECTIVE

We analyze phototherapy rates after implementation of a Hyperbilirubinemia Clinical Pathway (HCP), which placed full-term ABOi DAT negative newborns on the low risk phototherapy nomogram, rather than medium risk, as previously done.

STUDY DESIGN

A chart review was performed for ABOi newborns born ≥36 weeks gestation between January 2020 and October 2021. Primary outcome measures were rates of phototherapy across pre- and post-intervention groups and among DAT negative newborns.

RESULTS

There was an increased proportion of newborns assigned to the low risk curve after the intervention. There were no significant differences in phototherapy rates among the intervention groups, although there was a non-significant decrease in phototherapy rates among DAT negative newborns after the intervention. There were no increases in adverse outcomes.

CONCLUSIONS

Providers adhered to the guidelines after implementation of the HCP. ABOi DAT negative newborns can be viewed as low risk for hyperbilirubinemia requiring phototherapy.

摘要

目的

我们分析了实施高胆红素血症临床路径(HCP)后的光疗率,该路径将足月 ABOiDAT 阴性新生儿置于低风险光疗列线图上,而不是像以前那样置于中风险。

研究设计

对 2020 年 1 月至 2021 年 10 月期间出生胎龄≥36 周的 ABOi 新生儿进行了图表回顾。主要结局指标是干预前后的光疗率以及 DAT 阴性新生儿的光疗率。

结果

干预后,更多的新生儿被分配到低风险曲线。干预组之间的光疗率没有显著差异,尽管干预后 DAT 阴性新生儿的光疗率有非显著下降。没有不良结局的增加。

结论

提供者在实施 HCP 后遵守了指南。ABOiDAT 阴性新生儿可视为需要光疗的高胆红素血症低风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99f5/10034253/67a63473db14/41372_2023_1650_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99f5/10034253/23f48bb7ecb9/41372_2023_1650_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99f5/10034253/67a63473db14/41372_2023_1650_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99f5/10034253/23f48bb7ecb9/41372_2023_1650_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99f5/10034253/67a63473db14/41372_2023_1650_Fig2_HTML.jpg

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Pediatrics. 2022 Sep 1;150(3). doi: 10.1542/peds.2022-058859.
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Decreasing Laboratory Testing for Neonatal Jaundice Through Revision of a Clinical Practice Pathway.通过修订临床实践路径来减少新生儿黄疸的实验室检测。
Hosp Pediatr. 2022 Feb 1;12(2):e67-e72. doi: 10.1542/hpeds.2021-006019.
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遗传性血栓性血小板减少性紫癜。
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Efficacy of Subthreshold Newborn Phototherapy During the Birth Hospitalization in Preventing Readmission for Phototherapy.亚阈值新生儿光疗在预防因光疗再次入院方面的疗效。
JAMA Pediatr. 2018 Apr 1;172(4):378-385. doi: 10.1001/jamapediatrics.2017.5630.
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Neonatal Jaundice: Improved Quality and Cost Savings After Implementation of a Standard Pathway.新生儿黄疸:实施标准流程后的质量提高和成本节约。
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