Bai Huixin, Jiang Shanfeng, Liu Jincai, Tian Ye, Zheng Xiaohui, Wang Siwang, Xie Yanhua, Li Yao, Jia Pu
Department of Life Science and Medicine, Northwest University, Xi'an, China.
School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.
Front Plant Sci. 2023 Mar 7;14:1133062. doi: 10.3389/fpls.2023.1133062. eCollection 2023.
Mulberry ( L.) has a special significance in the history of agriculture and economic plant cultivation. Mulberry has strong environmental adaptability, a wide planting range, and abundant output. It is not only an important resource for silkworm breeding but also a raw ingredient for various foods and has great potential for the development of biological resources. The bioactivities of mulberry in different planting areas are not the same, which is an obstacle to the development of mulberry. This study collected information on the planting conditions of mulberry branches in 12 planting areas, such as altitude, temperature difference, and precipitation. A comparison of the levels of 12 constituents of mulberry branches from mulberry grown in different planting areas was then made. An model was used to study the bioactivities of mulberry branches in the 12 planting areas, and mathematical analysis was used to explain the possible reasons for the differences in the composition and bioactivities of mulberry branches in different planting areas. After studying mulberry samples from 12 planting areas in China, it was found that a small temperature difference could affect the antiapoptotic effect of mulberry branch on microvascular endothelial cells by changing the levels and proportions of rutin, hyperoside, and morusin. Adequate irrigation can promote the antioxidation of the mulberry branch on microvascular endothelial cells by changing the levels and proportions of scopoletin and quercitrin. The results of the analysis of planting conditions and the levels of active constituents and their correlation with bioactivities support the improvement of mulberry planting conditions and have great significance in the rational development of mulberry resources. This is the first time that a mathematical analysis method was used to analyze the effects of planting conditions on mulberry biological activity.
桑（L.）在农业和经济作物种植史上具有特殊意义。桑树环境适应性强，种植范围广，产量丰富。它不仅是养蚕的重要资源，也是各种食品的原料，具有巨大的生物资源开发潜力。不同种植地区的桑树生物活性不尽相同，这是桑树发展的一个障碍。本研究收集了12个种植地区桑树枝条的种植条件信息，如海拔、温差和降水量。然后对不同种植地区桑树的桑树枝条中12种成分的含量进行了比较。采用一种模型研究了12个种植地区桑树枝条的生物活性，并运用数学分析解释了不同种植地区桑树枝条成分和生物活性差异的可能原因。在研究了中国12个种植地区的桑树样本后发现，较小的温差可通过改变芦丁、金丝桃苷和桑色素的含量及比例来影响桑树枝条对微血管内皮细胞的抗凋亡作用。充足的灌溉可通过改变东莨菪素和槲皮苷的含量及比例来促进桑树枝条对微血管内皮细胞的抗氧化作用。种植条件分析结果、活性成分含量及其与生物活性的相关性支持了改善桑树种植条件，对合理开发桑树资源具有重要意义。这是首次使用数学分析方法来分析种植条件对桑树生物活性的影响。
