Chung Esther H, Mebane Sloane, Harris Benjamin S, White Erin, Acharya Kelly S
Stanford Fertility and Reproductive Health Services, Department of Obstetrics and Gynecology, Stanford University, Sunnyvale.
Duke Fertility Center, Department of Obstetrics and Gynecology, Duke University, Durham, NC.
F S Rep. 2022 Dec 30;4(1):98-103. doi: 10.1016/j.xfre.2022.12.007. eCollection 2023 Mar.
To assess recall bias by evaluating how well female cancer survivors remember details regarding their cancer diagnosis, treatment, and fertility preservation (FP) counseling.Oncofertility literature cites recall bias as a pitfall of retrospective surveys, but limited data exist to quantify this bias.
Retrospective secondary analysis of cross-sectional survey data.
Single academic medical center.
Female oncology patients of reproductive age, 18-44 years old, at least 6 months past their last chemotherapy treatment.
Not applicable.
Recall of details surrounding cancer diagnosis and chemotherapy regimens, recall of FP counseling and ovarian reserve testing, and rates of chart-documented FP counseling.
In total, 117 patients completed the survey, with 112 verified via chart review. When asked to report the chemotherapy regimen, 57% (64 of the 112) marked "I don't know/prefer not to say." Regarding FP, 80% (90 of the 112) denied being offered counseling. Of the 37 (33%) who had documented FP conversations, 13 (35%) did not recall mention of fertility. Only 2 of 8 patients with ovarian reserve testing recalled this being performed at their initial visit. Multivariable logistic regression revealed older age was significantly associated with not being offered FP (odds ratio [OR] 0.87).
Our results confirm that the accuracy of oncology patients' reporting is limited by a poor recall, particularly regarding their specific chemotherapy regimen. More than 1 in 3 patients documented to have been offered FP counseling do not recall this discussion. Importantly, only one-third of cancer survivors had chart-documented FP counseling. Increased efforts are needed to ensure adequate follow-up beyond the initial visit.
通过评估女性癌症幸存者对其癌症诊断、治疗及生育力保存（FP）咨询细节的记忆程度来评估回忆偏倚。肿瘤生育学文献将回忆偏倚列为回顾性调查的一个缺陷，但用于量化这种偏倚的数据有限。
对横断面调查数据进行回顾性二次分析。
单一学术医疗中心。
年龄在18 - 44岁之间、末次化疗结束至少6个月的育龄期女性肿瘤患者。
不适用。
对癌症诊断和化疗方案相关细节的回忆、对FP咨询和卵巢储备检测的回忆以及病历记录的FP咨询率。
共有117名患者完成了调查，其中112名经病历审查核实。当被要求报告化疗方案时，57%（112名中的64名）选择“我不知道/不想说”。关于FP，80%（112名中的90名）否认曾接受咨询。在有FP谈话记录的37名（33%）患者中，13名（35%）不记得曾提及生育问题。在8名进行过卵巢储备检测的患者中，只有2名记得在初次就诊时做过此项检测。多变量逻辑回归显示，年龄较大与未接受FP咨询显著相关（优势比[OR]为0.87）。
我们的结果证实，肿瘤患者报告的准确性受到回忆不佳的限制，尤其是关于其具体化疗方案。超过三分之一有病历记录显示接受过FP咨询的患者不记得有过这样的讨论。重要的是，只有三分之一的癌症幸存者有病历记录的FP咨询。需要加大力度确保在初次就诊后进行充分的随访。
