Majid Zain, Khan Shoaib Ahmed, Akbar Nishat, Khalid Muhammad Ali, Hanif Farina Muhammad, Laeeq Syed Mudassir, Luck Nasir Hassan
Department of Hepatogastroenterology, Sindh Institute of Urology & Transplantation (SIUT), Karachi, Pakistan.
Euroasian J Hepatogastroenterol. 2022 Jul-Dec;12(2):77-80. doi: 10.5005/jp-journals-10018-1378.
Variceal hemorrhage is a serious consequence of patients having chronic liver disease (CLD). Various scores exist that predict the outcome for non-variceal bleed. However, only a few scores evaluate patients with variceal bleed. We, in our study, evaluated 48 cirrhotics who presented with variceal gastrointestinal (GI) bleed over a period of 3 months. Majority of these were males and the most common etiology was hepatitis C infection. The main presenting complaints were hematemesis seen in 39.6% followed by hematemesis and melena in 31.25%. Most bleeding episodes were secured via banding in 62.5% followed by injection of histoacryl in 12.5%. Finally, Child-Turcotte-Pugh (CTP), model for end-stage liver disease (MELD), albumin-to-bilirubin (ALBI), and the ABC score were applied and none correlated with the presence of esophageal varices. However, the ALBI score did correlate with the presence of tachycardia in our study, a pertinent sign of upper GI bleed.
Majid Z, Khan SA, Akbar N, . The Use of Albumin-to-bilirubin Score in Predicting Variceal Bleed: A Pilot Study from Pakistan. Euroasian J Hepato-Gastroenterol 2022;12(2):77-80.
静脉曲张出血是慢性肝病(CLD)患者的严重后果。存在多种预测非静脉曲张出血结局的评分。然而,只有少数评分用于评估静脉曲张出血患者。在我们的研究中,我们评估了48例在3个月内出现静脉曲张性胃肠道(GI)出血的肝硬化患者。这些患者大多数为男性,最常见的病因是丙型肝炎感染。主要的就诊主诉中,39.6%为呕血,其次31.25%为呕血和黑便。大多数出血事件通过套扎处理,占62.5%,其次是注射组织黏合剂,占12.5%。最后,应用了Child-Turcotte-Pugh(CTP)评分、终末期肝病模型(MELD)评分、白蛋白与胆红素比值(ALBI)评分以及ABC评分,结果发现这些评分均与食管静脉曲张的存在无关。然而,在我们的研究中,ALBI评分确实与心动过速的存在相关,心动过速是上消化道出血的一个相关体征。
Majid Z, Khan SA, Akbar N, 。白蛋白与胆红素比值评分在预测静脉曲张出血中的应用:来自巴基斯坦的一项初步研究。《欧亚肝脏胃肠病学杂志》2022年;12(2):77 - 80。