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艾司洛尔并非解决方案:伴有心房颤动的甲状腺风暴

Esmolol Is Not the Solution: Thyroid Storm With Atrial Fibrillation.

作者信息

Herzallah Zaid N, Gupta Shreya, Abdulhamid Maryam D, Muhammed Noori Omar Q

机构信息

Emergency Medicine, Rashid Hospital Trauma Center/Dubai Health Authority (DHA), Dubai, ARE.

Internal Medicine, Rashid Hospital Trauma Center/Dubai Health Authority (DHA), Dubai, ARE.

出版信息

Cureus. 2023 Feb 20;15(2):e35201. doi: 10.7759/cureus.35201. eCollection 2023 Feb.

DOI:10.7759/cureus.35201
PMID:36960263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10031383/
Abstract

Thyroid storm is a challenging medical emergency that requires urgent assessment and management in a timely manner. In this article, we report on a case of a 37-year-old female who presented to the emergency department with a thyroid storm complicated by atrial fibrillation (AF) with a rapid ventricular response with no clinical signs of heart failure. As part of her medical management to rate control her AF, she was started on an infusion of a short-acting beta blocker, esmolol, and shortly after, she developed cardiac arrest. This is the second case report published to highlight the significant response (cardiac arrest) of patients with thyroid storm complicated by AF to a low dose esmolol infusion as part of their medical management.

摘要

甲状腺危象是一种具有挑战性的医疗急症,需要及时进行紧急评估和处理。在本文中,我们报告了一例37岁女性病例,该患者因甲状腺危象合并房颤伴快速心室反应就诊于急诊科,且无心力衰竭的临床体征。作为其房颤心率控制治疗的一部分,她开始静脉输注短效β受体阻滞剂艾司洛尔,不久后发生心脏骤停。这是第二篇病例报告,旨在强调甲状腺危象合并房颤患者在接受低剂量艾司洛尔静脉输注作为治疗一部分时出现的显著反应(心脏骤停)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0547/10031383/53a80583363c/cureus-0015-00000035201-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0547/10031383/d63ac2285a16/cureus-0015-00000035201-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0547/10031383/53a80583363c/cureus-0015-00000035201-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0547/10031383/d63ac2285a16/cureus-0015-00000035201-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0547/10031383/53a80583363c/cureus-0015-00000035201-i02.jpg

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本文引用的文献

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Cardiovascular Collapse Secondary to Beta-Blocker Administration in a Setting of Coexisting Thyroid Storm and Atrial Fibrillation: A Case Report.甲状腺风暴和心房颤动并存情况下因使用β受体阻滞剂继发心血管虚脱:一例报告
Cureus. 2022 Sep 19;14(9):e29321. doi: 10.7759/cureus.29321. eCollection 2022 Sep.
2
Management of Cardiogenic Shock due to Thyrotoxicosis: A Systematic Literature Review.甲状腺毒症性心原性休克的治疗:系统文献回顾。
Curr Cardiol Rev. 2020;16(4):326-332. doi: 10.2174/1573403X16666200313103657.
3
Propranolol-Induced Circulatory Collapse in a Patient With Thyroid Crisis and Underlying Thyrocardiac Disease: A Word of Caution.
普萘洛尔诱发甲状腺危象合并潜在甲状腺心脏病患者循环衰竭:一则警示
J Investig Med High Impact Case Rep. 2017 Dec 20;5(4):2324709617747903. doi: 10.1177/2324709617747903. eCollection 2017 Oct-Dec.
4
Hyperthyroidism and thyrotoxicosis.甲状腺功能亢进症与甲状腺毒症
Emerg Med Clin North Am. 2014 May;32(2):277-92. doi: 10.1016/j.emc.2013.12.001. Epub 2014 Mar 15.
5
The mechanisms of atrial fibrillation in hyperthyroidism.甲状腺功能亢进症中心房颤动的机制。
Thyroid Res. 2009 Apr 2;2(1):4. doi: 10.1186/1756-6614-2-4.
6
Thyrotoxic cardiac disease.甲状腺毒症性心脏病
Curr Heart Fail Rep. 2008 Sep;5(3):170-6. doi: 10.1007/s11897-008-0026-9.
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Thyroid disease and the heart.甲状腺疾病与心脏
Circulation. 2007 Oct 9;116(15):1725-35. doi: 10.1161/CIRCULATIONAHA.106.678326.
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Cardiovascular collapse associated with beta blockade in thyroid storm.甲状腺危象中与β受体阻滞剂相关的心血管衰竭。
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9
When the storm passes unnoticed--a case series of thyroid storm.当风暴悄然过去——一组甲状腺风暴病例
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Chest. 2000 Sep;118(3):877-9. doi: 10.1378/chest.118.3.877.