Khan Omar Abdallah, Sesma Gorka, Alawi Abeer, AlWazae Manal
Pediatric Ophthalmology and Strabismus Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Clin Ophthalmol. 2023 Mar 16;17:897-906. doi: 10.2147/OPTH.S403016. eCollection 2023.
To compare the outcomes of non-penetrating deep sclerectomy (NPDS) for primary congenital glaucoma (PCG) performed by experienced vs trainee surgeons.
This retrospective cohort study was conducted in 2022 in Saudi Arabia. Consultants (Gr-1) and trainee pediatric ophthalmologists (Gr-2) performed NPDS on pediatric patients with PCG. Success was defined as an intraocular pressure (IOP) less than 21 mmHg at 6 months after surgery. Complications, glaucoma medications, and additional procedures were also observed in the two groups.
Gr-1 and Gr-2 operated on 14 and 39 eyes with PCG, respectively. The absolute success rates were 90.9% (95% confidence interval [CI]: 73.9, 100) in Gr-1 and 96.7% (95% CI: 90.2, 100) in Gr-2 (odds Ratio=1.1; 95% CI: 0.87, 1.3; P=0.54). Survival analysis suggested that the failure rate in the first 6 months after NPDS was not significantly different between the two groups (hazard ratio=1.45; 95% CI: 0.13, 16.0; P=0.767). The complications included hypotony (2 cases), vitreous hemorrhage (1 case), and total flap penetration (1 case). Only one eye in Gr-2 needed glaucoma medication after surgery. There was no significant difference in the success rates of one surgeon before and after training (P=0.43). The age (P=0.59) and sex (P=0.77) of patients, type of surgeon (P=0.94), and preoperative IOP (P=0.59) were not significant predictors of a stable IOP at 6 months after NPDS.
At 6 months after NPDS surgery performed by experienced and trainee pediatric ophthalmologists, the outcomes (stabilization of IOP) were similar between the two groups.
比较经验丰富的外科医生与实习医生进行非穿透性深层巩膜切除术(NPDS)治疗原发性先天性青光眼(PCG)的效果。
这项回顾性队列研究于2022年在沙特阿拉伯进行。顾问医生(第1组)和实习儿科眼科医生(第2组)对患有PCG的儿科患者进行NPDS手术。成功定义为术后6个月眼压(IOP)低于21 mmHg。还观察了两组的并发症、青光眼药物使用情况及额外的手术操作。
第1组和第2组分别对14只和39只患有PCG的眼睛进行了手术。第1组的绝对成功率为90.9%(95%置信区间[CI]:73.9,100),第2组为96.7%(95% CI:90.2,100)(优势比=1.1;95% CI:0.87,1.3;P = 0.54)。生存分析表明,NPDS术后前6个月两组的失败率无显著差异(风险比=1.45;95% CI:0.13,16.0;P = 0.767)。并发症包括低眼压(2例)、玻璃体积血(1例)和瓣全层穿透(1例)。第2组术后仅1只眼需要使用青光眼药物。一名外科医生培训前后的成功率无显著差异(P = 0.43)。患者的年龄(P = 0.59)、性别(P = 0.77)、外科医生类型(P = 0.94)和术前眼压(P = 0.59)均不是NPDS术后6个月眼压稳定的显著预测因素。
经验丰富的儿科眼科医生和实习医生进行NPDS手术后6个月,两组的治疗效果(眼压稳定)相似。