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美国医学研究所(IOM)建议对美国女性孕期体重增加的影响:对2011 - 2019年出生记录的分析

The impact of IOM recommendations on gestational weight gain among US women: An analysis of birth records during 2011-2019.

作者信息

Tennekoon Vidhura S

机构信息

Department of Economics, School of Liberal Arts, Indiana University Purdue University Indianapolis (IUPUI), Indianapolis, Indiana, United States of America.

出版信息

PLOS Glob Public Health. 2022 Jul 21;2(7):e0000815. doi: 10.1371/journal.pgph.0000815. eCollection 2022.

Abstract

The prevailing guidelines of the Institute of Medicine (IOM) of United States on gestational weight gain (GWG) are based on women's prepregnancy body mass index (BMI) categories. Previous research has shown that the guidelines issued in 1990 and revised in 2009 had no effect. We investigate the effectiveness of new guidelines issued in 2009 analyzing the records of all singleton births in the U.S. during 2011-2019 (34.0 million observations). We use the discontinuity in recommended guidelines at the threshold values of BMI categories in a regression discontinuity (RD) research design to investigate the effect of IOM guidelines on GWG. We also use an RD analysis in a difference in difference (DID) framework where we compare the effect on women who had any prenatal care to others who did not receive prenatal care. The naïve RD estimator predicts an effect in the expected direction at the threshold BMI values of 18.5 and 25.0 but not at 30.0. After the DID based correction, the RD analyses show that the GWG, measured in kg, drop at the BMI values of 18.5, 25.0 and 30.0 by 0.189 [CI: 0.341, 0.037], 0.085 [CI: 0.179, -0.009] and 0.200 [CI: 0.328, 0.072] respectively when the midpoint of the recommended range in kg drops by 1.5, 4.5 and 2.25. This implies a responsiveness of 12.6%, 1.9% and 8.9% respectively to changes in guidelines at these BMI values. The findings show that the national guidelines have induced some behavioral changes among US women during their pregnancy resulting in a change in GWG in the expected direction. However, the magnitude of the change has not been large compared to the expectations, implying that the existing mechanisms to implement these guidelines have not been sufficiently strong.

摘要

美国医学研究所(IOM)关于孕期体重增加(GWG)的现行指南是基于女性孕前体重指数(BMI)类别制定的。先前的研究表明,1990年发布并于2009年修订的指南没有效果。我们通过分析2011 - 2019年美国所有单胎分娩记录(3400万条观测数据)来研究2009年发布的新指南的有效性。我们在回归断点(RD)研究设计中利用BMI类别阈值处推荐指南的不连续性,来研究IOM指南对GWG的影响。我们还在差异中的差异(DID)框架下进行RD分析,比较对接受过任何产前护理的女性与未接受产前护理的女性的影响。朴素的RD估计量在BMI阈值18.5和25.0处预测出了预期方向的影响,但在30.0处没有。经过基于DID的校正后,RD分析表明,当以千克为单位的推荐范围中点分别下降1.5、4.5和2.25时,在BMI值18.5、25.0和30.0处,以千克衡量的GWG分别下降0.189[置信区间:0.341,0.037]、0.085[置信区间:0.179, - 0.009]和0.200[置信区间:0.328,0.072]。这意味着在这些BMI值下,对指南变化的响应率分别为12.6%、1.9%和8.9%。研究结果表明,国家指南在美国女性孕期引发了一些行为变化,导致GWG朝着预期方向改变。然而,与预期相比,变化幅度不大这意味着实施这些指南的现有机制不够有力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ead/10021552/fe107cfec608/pgph.0000815.g001.jpg

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